Growth and Safety Clinical Trial on a New Infant Formula

NCT ID: NCT05508750

Last Updated: 2024-01-17

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

420 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-09-21

Study Completion Date

2024-01-02

Brief Summary

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The aim of this study is to assess age-appropriate growth of healthy infants fed a new infant formula. In this randomized, controlled trial, healthy, term, formula-fed infants will be randomized to one of two infant formulas: a standard, commercially-available infant formula for term infants or the new infant formula for term infants for 16 weeks. A reference group of human milk-fed infants will also be enrolled. This study is designed in accordance with Good Clinical Practice guidelines and the requirements of the Code of Federal Regulations, 21CFR106.96. This study allows caregivers to participate completely from the comfort of their own home.

Detailed Description

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Conditions

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Weight Gain

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

A decentralized, randomized, controlled trial of healthy term breastfed and formula-fed infants for 16 weeks
Primary Study Purpose

OTHER

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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New Infant Formula

New infant formula for healthy term infants

Group Type EXPERIMENTAL

New Infant Formula

Intervention Type OTHER

New infant formula fed daily ad libitum

Commercial Infant Formula

Standard, commercially available infant formula for healthy term infants

Group Type ACTIVE_COMPARATOR

Commercial Infant Formula

Intervention Type OTHER

Commercially available infant formula fed daily ad libitum

Human Milk

Breastfed infants serve as a reference group

Group Type NO_INTERVENTION

No interventions assigned to this group

Interventions

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New Infant Formula

New infant formula fed daily ad libitum

Intervention Type OTHER

Commercial Infant Formula

Commercially available infant formula fed daily ad libitum

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Normal term infant (37-42 weeks gestation at birth)
* Infant \<15 (+3) days of age at first study feeding, Birth constitutes day 0
* Infant birth weight of ≥2500 g (5.5 lbs.)
* Healthy Infant
* Caregiver who has previously decided to exclusively feed infant formula or exclusively breastfeed and is willing to continue with current feeding method throughout the study (breastfeeding or formula feeding)
* Caregiver willing to conform to protocol requirements (e.g. measuring, feeding, completion of food intake and tolerance diaries, and reporting of AEs)
* Caregiver willing and able to sign informed consent

Exclusion Criteria

* Infant born in multiple birth (i.e., twins, triplets, etc.)
* Infant born with medical complications (e.g., neurological, cerebral palsy, etc.)
* Infant with family history (parents or siblings) of confirmed Milk or Soy allergies
* Infant with failure to thrive, fever, any GI tract abnormalities (e.g., short gut, gastroesophageal reflux, etc.), any congenital illness or malformation that may affect infant feeding or normal growth
* Caregiver intent to feed non-study formula or solid food during the study
Minimum Eligible Age

0 Days

Maximum Eligible Age

14 Days

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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IQVIA RDS Inc.

INDUSTRY

Sponsor Role collaborator

ObvioHealth

INDUSTRY

Sponsor Role collaborator

Jovie USA, LLC

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Parth Shah, MD FAPCR

Role: PRINCIPAL_INVESTIGATOR

ObvioHealth

Dawn Ross, Director Clinical Project Management

Role: STUDY_DIRECTOR

IQVIA RDS Inc.

Locations

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ObvioHealth

New York, New York, United States

Site Status

Countries

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United States

Other Identifiers

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IQV-JOV-001

Identifier Type: -

Identifier Source: org_study_id

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