Telecommunication Technology-based Online Survey

NCT ID: NCT06159699

Last Updated: 2026-01-27

Basic Information

• Recruitment Status: RECRUITING
• Total Enrollment: 2000 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2022-12-02
• Study Completion Date: 2028-12-31

Brief Summary

The aim of this study is to identify and assess new health-associated risk factors, including clinical-pharmacological risk factors. The cohort is built using telecommunication approaches. The associations between clinical-pharmacological, social, demographic, behavioral, and environmental characteristics will be assessed. The continuous depersonalized online survey is performed using the original informational resources in the form of specially designed web-site aimed at identification and assessment of population-based pharmacotherapy patterns including characteristics of self-medication, biologically active food supplement intake, polypharmacy, and adverse drug-drug interactions in the people residing in the ecological conditions of various regions of the country. The invitations to participate in the online survey are sent via the SMS messages using the SMS-Target tool provided by OOO T2 Mobile Company. The survey is performed online at www.zdorov.tpu.ru and www.zdorov.expert both specifically designed for questionnaire publication and data accumulation.

Detailed Description

Polypharmacy-associated serious drug-drug interactions and adverse drug reactions may increase the risk of morbidity and mortality in the population, especially in cardiovascular patients. Insufficient patient compliance to treatment and potential self-medication overlap with behavioral, psychosocial, demographic, and environmental conditions and pose new challenges for the population striving to achieve active longevity. These issues have been especially relevant during and after the COVID-19 pandemic. The aim of this study is to identify and assess new health-associated risk factors, including clinical-pharmacological risk factors. Telecommunication approaches are used for the formation of study cohort. The associations between clinical-pharmacological, social, demographic, behavioral, and environmental characteristics of study cohort will be assessed. The continuous depersonalized online survey is performed using the original informational resource in the form of specially designed web-site aimed at identification and assessment of population-based pharmacotherapy patterns including characteristics of self-medication, biologically active food supplement intake, polypharmacy, and adverse drug-drug interactions in the people residing in the ecological conditions of various regions of the country. The acquired data may lay a foundation for the development decision support system for control of previously unrecognized or poorly recognized risk factors. The study will enroll as least 2000 respondents aged 18 years and older. The invitations to participate in the online survey are sent via the SMS messages using the SMS-Target tool provided by OOO T2 Mobile Company. The survey is performed online at www.zdorov.tpu.ru and www.zdorov.expert both specifically designed for questionnaire publication and data accumulation. Both websites have built-in functionality for downloading survey results in tabular format (.xls, .csv). All the respondents are required to sign the informed consent form electronically according to local legislation and international standards of ethical research. Considering that no physical medical examinations or interventions are involved in the study, and all data undergo complete depersonalization, participation in this study does not pose any risks for respondents. Financial support for the study is provided by the Russian Science Foundation (project No. 22-15-00313). Respondents will not be covered by insurance due to the non-interventional nature of the study.

Conditions

Risk Factors; Polypharmacy; Drug Interactions; Self Medication; COVID-19

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: CROSS_SECTIONAL

Study Groups

Non-structured population

The respondent will represent the non-structured population of the Russian Federation invited to participate in the study using the SMS-Target tool provided by OOO T2 Mobile Company.

Online Survey

Intervention Type: OTHER

The participants of the study undergo the online survey at www.zdorov.tpu.ru and www.zdorov.expert.

Genetic Testing

Intervention Type: DIAGNOSTIC_TEST

Genetic testing will be performed in subgroup of survey respondents willing to participate in the study of polymorphisms of genes involved in drug metabolism or affecting biological effects of medications including CYP2D6, ACE, UGT1A1, CYP2C9, and CYP2C19.

Interventions

Online Survey

The participants of the study undergo the online survey at www.zdorov.tpu.ru and www.zdorov.expert.

Intervention Type: OTHER

Genetic Testing

Genetic testing will be performed in subgroup of survey respondents willing to participate in the study of polymorphisms of genes involved in drug metabolism or affecting biological effects of medications including CYP2D6, ACE, UGT1A1, CYP2C9, and CYP2C19.

Intervention Type: DIAGNOSTIC_TEST

Other Intervention Names

Telecommunication-Based Survey; Genetic Polymorphisms of Drug-Metabolizing Enzymes

Eligibility Criteria

Inclusion Criteria

• age of 18 years and older
• signing the informed concent form online
• completion of the entire questionnaire

Exclusion Criteria

• age under 18 years
• refuse to sign the informed concent form

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: Yes

Sponsors

Tomsk National Research Medical Center of the Russian Academy of Sciences

OTHER

Sponsor Role: lead

Responsible Party

Nina D. Anfinogenova

Principal Investigator

Responsibility Role: PRINCIPAL_INVESTIGATOR

Principal Investigators

Nina D Anfinogenova, PhD

Role: PRINCIPAL_INVESTIGATOR

Tomsk NRMC

Locations

Tomsk National Research Medical Center, Russian Academy of Sciences

Tomsk, , Russia

Site Status: RECRUITING

Countries

Russia

Central Contacts

Nina D Anfinogenova, PhD

Role: CONTACT

anfiyj@gmail.com

+73822554111

Facility Contacts

Nina D Anfinogenova, PhD

Role: primary

anfiyj@gmail.com

+73822554111

Other Identifiers

CRI-248

Identifier Type: -

Identifier Source: org_study_id