Risk Factors at Chronic Non-communicable Diseases in People of Working Age

NCT ID: NCT06812767

Last Updated: 2025-02-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ENROLLING_BY_INVITATION

Total Enrollment

2000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2025-04-30

Study Completion Date

2026-04-30

Brief Summary

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Objectives: to study the clinical and demographic characteristics of working age persons, to highlight the main factors of non-communicable diseases (NCDs), to identify NCDs with physical examination, laboratory tests, electrocardiography and ultrasound imaging, to develop a corporate prevention program for the company to reduce the risk of complications of NCDs.

Research stages:

1. Questionnaire to identify socio-demographic, behavioral, hereditary, psycho-emotional risk factors of NCDs
2. Laboratory tests (analysis of glucose and cholesterol in the capillary blood, detection of microalbuminuria), diagnostic tests (electrocardiography, and carotid artery ultrasound)
3. Evaluation of the results of questionnaires and surveys. Recommendations for lifestyle modification and follow-up in a local healthcare department

Detailed Description

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Currently the emphasis in preventive medicine is also on health of the working population, which is a key state policy in the Russian Federation. Health of working citizens is an important factor in the development and safety of the production sector, but it is also the key to health and well-being of all other groups - children and older generations - that is, in fact, the fundamental factor for social development. Therefore, the integration of health-saving technologies into all areas of working life, including production and work activities, is particularly important. In today's world, it is very important that everyone actively participate in the preservation the health of the individual and its high awareness. Awareness of risk factors for chronic non-communicable diseases and measures prevention throughout life is an important part of a healthy society. Monitoring the health of working citizens allows to predict the problem and take the necessary measures in a timely manner.

In the Russian Federation, medical screening is a complex system, including medical examination by physicians of several specialties and application of the necessary methods of examination to identify chronic non-communicable diseases and their risk factors at an early stage that are the main cause of disability and premature mortality in the country's population, and also to form health status groups and provide recommendations for patients. The examination is carried out once every three years and includes a set of methods of advanced examination to identify early on the most likely chronic non-communicable disease for a given age and gender. Regular checkups are the most important mass and highly effective medical technology of health savings.

The work of carrying out regular preventive examinations and check-ups is carried out by primary health care. Often the quality of such work is limited by manpower shortages, technological and logistical barriers. In modern conditions, these obstacles can be overcome by using mobile systems that include modern digital diagnostic technologies, Allow for more in-depth investigation and identification of risk factors not covered by the standard examination protocol. This will increase the coverage and detection of risk factors, which is an important component of the health saving of the working population

Conditions

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Chronic Non-communicable Disease

Study Design

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Observational Model Type

COHORT

Study Time Perspective

CROSS_SECTIONAL

Study Groups

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Persons without NCDs

Persons without known NCDs and not using any medication on a permanent basis

electrocardiography

Intervention Type DIAGNOSTIC_TEST

12 standard leads

analysis for glucose and cholesterol in the capillary blood

Intervention Type DIAGNOSTIC_TEST

express test

detection of microalbumuria

Intervention Type DIAGNOSTIC_TEST

express test

heart ultrasound examination

Intervention Type DIAGNOSTIC_TEST

Ultrasound examination with Lumify Handheld S4-1 Phased Array Ultrasound (Philips)

carotid artery ultrasound examination

Intervention Type DIAGNOSTIC_TEST

Ultrasound examination with Lumify Handheld L12-4 Linear Array Ultrasound (Philips)

Interventions

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electrocardiography

12 standard leads

Intervention Type DIAGNOSTIC_TEST

analysis for glucose and cholesterol in the capillary blood

express test

Intervention Type DIAGNOSTIC_TEST

detection of microalbumuria

express test

Intervention Type DIAGNOSTIC_TEST

heart ultrasound examination

Ultrasound examination with Lumify Handheld S4-1 Phased Array Ultrasound (Philips)

Intervention Type DIAGNOSTIC_TEST

carotid artery ultrasound examination

Ultrasound examination with Lumify Handheld L12-4 Linear Array Ultrasound (Philips)

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* employees of the company
* persons without NCDs diagnosis and not receiving permanent medication
* residents of the region of the Russian Federation where a factory with permanent or temporary registration is located

Exclusion Criteria

* refusal to sign informed consent
* any NCDs requiring constant medication
* active cancer
* pulmonary embolism
* valve defects of the heart (except secondary mitral regurgitation)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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National Medical Research Center for Therapy and Preventive Medicine

OTHER_GOV

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Olga Dzhioeva, MD, PhD

Role: STUDY_DIRECTOR

National Medical Research Center for Therapy and Preventive Medicine

Locations

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National Medical Research Center for Therapy and Preventive Medicine

Moscow, , Russia

Site Status

Countries

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Russia

Other Identifiers

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05-05/24

Identifier Type: -

Identifier Source: org_study_id

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