Tongzhou Cohort Study

NCT ID: NCT05156580

Last Updated: 2025-10-02

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

ACTIVE_NOT_RECRUITING

Total Enrollment

31080 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-07-01

Study Completion Date

2026-09-01

Brief Summary

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Long-term Impact of Overweight/Obesity and Hypertension on Cardiovascular Risk in Middle-aged and Elderly Adults

Detailed Description

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Overweight and obesity are major risk factors associated with the development of hypertension, poor blood pressure control, and adverse cardiovascular outcomes. However, evidence regarding the long-term impact of overweight/obesity and hypertension on cardiovascular risk in middle-aged and elderly populations remains limited. Therefore, the present study aims to evaluate the long-term effects of overweight/obesity and hypertension on cardiovascular risk in middle-aged and elderly adults.Additionally, a subgroup analysis will be conducted in participants with sarcopenia to assess the influence of blood pressure on prognosis, exploring potential interactions between muscle loss, hypertension, and cardiovascular outcomes.

Conditions

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Obesity Hypertension

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Study Groups

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Obese hypertensive group

Patients who were diagnosed with obesity (body mass index (BMI)≥28kg/m2) and hypertension (systolic blood pressure (SBP)/diastolic blood pressure (DBP) ≥ 140/90 mmHg).

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Overweight hypertensive group

Overweight patients (24 kg/m2≤BMI≤28 kg/m2) diagnosed with hypertension (SBP/DBP≥140/90 mmHg).

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Lean hypertensive group

Lean patients (BMI ≤ 24 kg/m2) diagnosed with hypertension (SBP/DBP ≥ 140/90 mmHg).

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Lean normotensive

Lean patients (BMI ≤ 24 kg/m2) diagnosed with normotensive (SBP/DBP \< 140/90 mmHg).

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Overweight normotensive

Overweight patients (24 kg/m2≤BMI≤28 kg/m2) diagnosed with normotensive (SBP/DBP\<140/90 mmHg)

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Obese normotensive

Patients who were diagnosed with obesity (BMI≥28kg/m2) and normotensive (SBP/DBP\<140/90 mmHg).

No intervention

Intervention Type OTHER

This is an observational study without any intervention

Interventions

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No intervention

This is an observational study without any intervention

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Ages of ≥ 45 years
* Participants from routine health examinations at Tongzhou Community Health Service Center
* Availability for follow-up until 2026
* No major barriers to provide written consent

Exclusion Criteria

* NA
Minimum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Beijing Tongzhou Yongshun Community Health Service

UNKNOWN

Sponsor Role collaborator

Beijing Tongzhou Lucheng Community Health Service

UNKNOWN

Sponsor Role collaborator

Beijing Tongzhou Xuxinzhuang Community Health Service

UNKNOWN

Sponsor Role collaborator

Beijing Friendship Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Rongchong Huang, M.D.

Role: PRINCIPAL_INVESTIGATOR

Beijing Friendship Hospital

Locations

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Beijing Friendship Hospital, Capital Medical University

Beijing, Beijing Municipality, China

Site Status

Countries

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China

Other Identifiers

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2021-P2-163-01

Identifier Type: -

Identifier Source: org_study_id

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