Tianshan Community Cohort Establishment and Follow-up

NCT ID: NCT07207863

Last Updated: 2025-10-06

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

1000000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2016-01-01

Study Completion Date

2035-12-31

Brief Summary

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This population-based cohort study on disease prevention and health promotion was established in northwest China, leveraging data from routine annual health examinations. Initiated in January 2016, the cohort enrolled nearly all residents aged 18 years and older who were registered at community healthcare centers. The program was developed to provide a comprehensive framework for disease prevention and community health promotion, with the aim of producing population-based evidence across a broad spectrum of diseases in the general population. At baseline, data were collected on participant demographics, medical and family histories, disability status, living environment, and blood biochemical parameters. Follow-up information is primarily obtained through chronic disease management programs, annual health examinations, and electrical health records. Cause-specific mortality is ascertained from local death registration systems. Biological specimens, questionnaire data, and electrical health records are systematically archived in the Biobank and Big Data Center of the People's Hospital of Xinjiang Uygur Autonomous Region.

Detailed Description

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This research is conducted through population-based health examinations among residents in northwest China. By providing annual health assessments, structured health education, and community-based health promotion activities, the study aims to enhance health awareness, identify determinants of disease, implement targeted interventions to improve lifestyle behaviors, reduce modifiable risk factors, and promote overall community health.

The cohort integrates data from multiple sources- including health assessments, electronic health records, mortality registries, statistical yearbooks, and environmental datasets- encompassing a wide range of health-related information, such as demographics, lifestyle factors, family and personal medical histories, living conditions, enrollment in national public health services, physical examinations, laboratory tests, diagnostic assessments, disease outcomes, and cause-specific mortality. Event-driven follow-up data are obtained from 163 hospitals and 63 Traditional Chinese Medicine hospitals, covering all secondary and tertiary-level hospitals in the region. Inpatient data are systematically documented by qualified medical personnel and entered into an electronic health information system. All disease diagnoses are coded according to the 10th Revision of the International Classification of Diseases (ICD-10). Mortality data, including the timing and specific cause of death, are primarily obtained through local death registration systems.

Conditions

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Cohort Study Natural Population Northwest Region of China

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

1. Residents \>=18y
2. Permanent residents or individuals who have lived in the region for more than 5 years and are enrolled in local social security medical insurance
3. Residents without severe physical disability and capable of normal communication
4. Residents whose diseases and deaths are monitored and managed by the local health authorities
5. Residents who voluntarily participate and provide written informed consent

Exclusion Criteria

1. Temporary residents or floating population
2. Residents with severe health conditions that prevent participation in the study
3. Residents who are unwilling to undergo follow-up assessments for the study
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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People's Hospital of Hotan Prefecture

UNKNOWN

Sponsor Role collaborator

People's Hospital of Altay Prefecture

UNKNOWN

Sponsor Role collaborator

Luopu County People's Hospital of Hotan Prefecture

UNKNOWN

Sponsor Role collaborator

The First People's Hospital of Aksu Prefecture

UNKNOWN

Sponsor Role collaborator

Karamay Central Hospital of Xinjiang

UNKNOWN

Sponsor Role collaborator

People's Hospital of Kizilsu Kyrgyz Autonomous Prefecture

UNKNOWN

Sponsor Role collaborator

The Second People's Hospital of Kashgar Prefecture

UNKNOWN

Sponsor Role collaborator

RenJi Hospital

OTHER

Sponsor Role collaborator

People's Hospital of Xinjiang Uygur Autonomous Region

OTHER

Sponsor Role lead

Responsible Party

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Yining Yang

Prof.

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Yining Yang, Prof.

Role: PRINCIPAL_INVESTIGATOR

People's Hospital of Xinjiang Uygur Autonomous Region

Locations

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People's Hospital of Xinjiang Uygur Autonomous Region

Ürümqi, Xinjiang, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Qian Zhao, Dr.

Role: CONTACT

+86-13899993630

Facility Contacts

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Qian Zhao, Dr.

Role: primary

+8613899993630

Other Identifiers

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Tianshan2025

Identifier Type: -

Identifier Source: org_study_id

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