Effects of Pro2col Application on Health Outcomes

NCT ID: NCT06738641

Last Updated: 2025-09-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-10-06

Study Completion Date

2024-12-01

Brief Summary

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The purpose of this study is to test the effectiveness of a novel smartphone application (Pro2col Health) in regard to multiple health outcomes and health behaviors in healthy middle-aged adults.

Detailed Description

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This is a non-blinded randomized controlled pilot trial conducted over up to 8 weeks. Week 0 will involve baseline measurements and enrollment, Weeks 1-6 constitute the intervention, and Week 7 to 8 is reserved for post-testing. The study will enroll up to 200 participants, with a minimum of 50 participants who meet the inclusion criteria, and a minimum target of 20 participants completing the study in each group (experimental and control).

Following baseline testing and enrollment in the study, participants will be randomly assigned to either the control (CON) or experimental (PRO) group. The control group will receive subject-facing materials depicting current general activity recommendations as published by the American Heart Association (AHA) and current dietary guidelines provided by the United States Department of Agriculture (USDA). The experimental group will be enrolled in the Prime Health Technologies software (Pro2col), which provides a digital diagnostic score to calculate healthspan and biological age, along with AI and group community-based coaching dynamics. Subjects will be assigned a 6 week progressive protocol targeting improvements in daily activity levels, nutritional awareness, and overall lifestyle risk factors. Both groups will then be monitored by study staff throughout the duration of the intervention period with post-testing taking place following the last week of the experiment.

Conditions

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Health Behavior Nutrition, Healthy Activity, Motor

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Randomized controlled parallel study with pre- and post-measures
Primary Study Purpose

OTHER

Blinding Strategy

NONE

This is an open trial.

Study Groups

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Pro2col

The experimental group will be enrolled in the Prime Health Technologies software (Pro2col), which provides a digital diagnostic score to calculate healthspan and biological age, along with AI and group community-based coaching dynamics. Subjects will be assigned a 6 week progressive protocol targeting improvements in daily activity levels, nutritional awareness, and overall lifestyle risk factors.

Group Type EXPERIMENTAL

Pro2col Health

Intervention Type BEHAVIORAL

The Pro2col Health application is a smartphone application that provides users with health behavior guidance, personalized feedback, and assessments designed to estimate their current healthspan and biological age.

Control

The control group will receive subject-facing materials depicting current general activity recommendations as published by the American Heart Association (AHA) and current dietary guidelines provided by the United States Department of Agriculture (USDA).

Group Type ACTIVE_COMPARATOR

Control

Intervention Type BEHAVIORAL

The control group will receive subject-facing materials depicting current general activity recommendations as published by the American Heart Association (AHA) and current dietary guidelines provided by the United States Department of Agriculture (USDA).

Interventions

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Pro2col Health

The Pro2col Health application is a smartphone application that provides users with health behavior guidance, personalized feedback, and assessments designed to estimate their current healthspan and biological age.

Intervention Type BEHAVIORAL

Control

The control group will receive subject-facing materials depicting current general activity recommendations as published by the American Heart Association (AHA) and current dietary guidelines provided by the United States Department of Agriculture (USDA).

Intervention Type BEHAVIORAL

Eligibility Criteria

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Inclusion Criteria

* Male or female, aged 21-60 years.
* A BMI categorized as overweight (≥ 25) but not stage II obesity (≤ 35)
* Daily steps \< 5,000.
* Ownership of a smartphone device with either the Apple Health or Google Fit application.
* Willingness to carry their phone in their pocket or on their person at all times to track steps during study.
* Willing to download the Pro2col application and connect it with either the Apple Health or Google Fit application.
* Willingness to complete physical tasks including a timed one-mile walk/run, regular or modified push-ups to exhaustion, and chair get-ups to exhaustion.
* For the experimental group, subjects must be willing to follow the application protocol.
* Able to read, understand, sign and date the informed consent document (English only)
* Able and willing to comply with the scheduled visit(s) and study requirements.

Exclusion Criteria

* Currently taking (within the past 30 days) ergogenic dietary supplements including, creatine, protein, amino acids, or stimulants other than caffeine (yohimbe, ephedrine, etc.) Currently taking performance enhancing drugs (testosterone or other anabolic-androgenic steroids), human growth hormone, insulin, etc.
* History or current malignancy
* Receiving chemotherapy agents or radiation treatments
* Musculoskeletal disease (muscular dystrophy, arthritis, etc.)
* Recent (\<3-months) musculoskeletal injuries
* BMI \< 25 or \> 35 kg/m2
* Diagnosis of a terminal illness
* Use of prescription medications that influence body composition (i.e., prescription hormone therapies, etc.)
* History of alcohol abuse
* History or current drug abuse
* History or current diagnosis of depression.
* History or current diagnosis of suicidal thoughts/ideation.
* A score of ≥ 10 arbitrary units on the PHQ-9 during baseline testing.
* History or current cigarette smoke (including vaping) within the past 14 days from the screening visit
* Insulin-dependent diabetes and/or metformin use
* Chronic kidney or liver disease
* Has significant concurrent illnesses (controlled or uncontrolled), such as diabetes, lupus, epilepsy, or cardiac disorders, hepatitis B/C, HIV, serious mental health illness such as dementia or schizophrenia; psychiatric hospitalization in the past two years, or other, which in the opinion of the investigator, such conditions might be aggravated as a result of treatment
* The investigator feels that for any reason the subject is not eligible to participate in the study
* History of uncontrolled cardiovascular disease (i.e., myocardial infarction, hypertension, hypercholesterolemia, peripheral vascular disease, other)
* Developmental disability or cognitive impairment that would preclude adequate comprehension of the informed consent form and/or ability to follow study subject requirement and/or record the necessary study measurements
* A family member of the investigator or an employee of the investigator
* Participation in any other investigational study within 30 days prior to consent.
Minimum Eligible Age

21 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Applied Science & Performance Institute

INDUSTRY

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Applied Science and Performance Institute

Tampa, Florida, United States

Site Status

Countries

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United States

Provided Documents

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Document Type: Study Protocol and Statistical Analysis Plan

View Document

Other Identifiers

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P083124

Identifier Type: -

Identifier Source: org_study_id

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