Effects of Plant Polar Lipids on Glucose Tolerance

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

17 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-12-06

Study Completion Date

2024-01-25

Brief Summary

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In this randomized controlled trial, two different plant polar lipids are investigated with respect to their potential to affect acute and second meal glucose tolerance and appetite sensations. The effects are compared with a common non-polar commercial oil. The lipids are consumed spread on a white wheat bread. A white wheat bread without added lipids is included as a control product. The test products are consumed at breakfast, and test variables are investigated in the postprandial period after the test breakfast and also after a second meal standard lunch.

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Detailed Description

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Conditions

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Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants

Due to the character of the test products, the masking is partial

Study Groups

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Polar lipid 1

15 g Plant polar lip 1 consumed with a white wheat bread including 50 g available carbohydrates

Group Type EXPERIMENTAL

Polar lipid 1

Intervention Type DIETARY_SUPPLEMENT

15g plant polar lipids from plant source 1. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

Polar lipid 2

15 g Plant polar lipids 2 consumed with a white wheat bread including 50 g available carbohydrates

Group Type EXPERIMENTAL

Polar lipid 2

Intervention Type DIETARY_SUPPLEMENT

15g plant polar lipids from plant source 2. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

non-polar lipids

15 g commonly consumed non-polar lipids consumed with a white wheat bread including 50 g available carbohydrates

Group Type ACTIVE_COMPARATOR

Non-polar lipids

Intervention Type DIETARY_SUPPLEMENT

15g non-polar plant lipids from plant source 1. The lipids supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

no lipids

A white wheat bread including 50 g available carbohydrates

Group Type PLACEBO_COMPARATOR

No lipids

Intervention Type OTHER

A commercial white wheat flour bread as a source of available carbohydrates (50 g), without added lipids.

Interventions

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Polar lipid 1

15g plant polar lipids from plant source 1. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

Intervention Type DIETARY_SUPPLEMENT

Polar lipid 2

15g plant polar lipids from plant source 2. The lipid supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

Intervention Type DIETARY_SUPPLEMENT

Non-polar lipids

15g non-polar plant lipids from plant source 1. The lipids supplement is consumed spread on a commercial white wheat flour bread as a source of available carbohydrates (50 g).

Intervention Type DIETARY_SUPPLEMENT

No lipids

A commercial white wheat flour bread as a source of available carbohydrates (50 g), without added lipids.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Apparently healthy men and women
* non-smokers
* between 20-40 years of age
* BMI between 18,5-30 kg/m2
* No known metabolic disorders or food allergies.
* The test subjects should follow a normal diet in accordance with the Nordic Nutrition Recommendations.

Exclusion Criteria

* Fasting blood glucose ≥6.1 mmol/L
* Use of antibiotics or probiotics in the last three months or during the study period.
* Smoking
* Blood donation during the last two months and during the study.
* Food allergies or food intolerances
* Cardiovascular diseases
* Metabolic diseases
* Inflammatory bowel diseases.

Minimum Eligible Age

20 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes