The Effects of Beta-glucan Enriched Oatcake Consumption on Metabolic Disease Risk Factors
NCT ID: NCT02615444
Last Updated: 2016-09-27
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
90 participants
INTERVENTIONAL
2015-10-31
2016-12-31
Brief Summary
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Detailed Description
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Oat beta-glucan has been incorporated into a novel oatcake product manufactured by Nairn's Oatcakes Ltd. Consumption of the oatcake products will deliver enough oat-beta glucan to the diet to meet European Food Safety Authority health claims for lowering blood cholesterol and reducing post-prandial glycaemic responses.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
PREVENTION
DOUBLE
Study Groups
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Beta-glucan enriched oatcake
Oatcakes which have been enriched with beta-glucan. Each participant will consume 5 oatcakes daily in order to ingest 4g of oat-beta glucan.
Beta-glucan enriched oatcake
5 oatcakes enriched with oat beta-glucan will be consumed daily for six weeks
Isocaloric control
Control: Wheat based snack, equicaloric and matched to intervention product for macronutrient content. Contains no oat-beta glucan. Each participant will consume 6.5 Krackawheats daily.
Isocaloric control
6.5 wheat based control snacks without beta-glucan will be consumed daily for six weeks
Interventions
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Beta-glucan enriched oatcake
5 oatcakes enriched with oat beta-glucan will be consumed daily for six weeks
Isocaloric control
6.5 wheat based control snacks without beta-glucan will be consumed daily for six weeks
Eligibility Criteria
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Inclusion Criteria
* Waist circumference measurements of ≥94cm for males and 80cm for females, or a body mass index of ≥30kg/m2
* Individuals who are able to provide informed consent
Exclusion Criteria
* Smokers
* Individuals who suffer from, or taking medication for, cardiovascular or gastro-intestinal disease
* Impaired glucose tolerance/Diabetes mellitus
* Pregnancy or breastfeeding
* Those who have high dietary fibre intakes (\>20g/day)
* Known food allergies to oats, wheat, lactose, or sesame seeds
18 Years
ALL
Yes
Sponsors
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Queen Margaret University
OTHER
Responsible Party
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Suzanne Zaremba
PhD Student
Principal Investigators
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Suzanne Zaremba
Role: STUDY_CHAIR
Queen Margaret University
Locations
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Queen Margaret University, Edinburgh
Musselburgh, East Lothain, United Kingdom
Countries
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References
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Pouliot MC, Despres JP, Lemieux S, Moorjani S, Bouchard C, Tremblay A, Nadeau A, Lupien PJ. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol. 1994 Mar 1;73(7):460-8. doi: 10.1016/0002-9149(94)90676-9.
Lissner L, Lindroos AK, Sjostrom L. Swedish obese subjects (SOS): an obesity intervention study with a nutritional perspective. Eur J Clin Nutr. 1998 May;52(5):316-22. doi: 10.1038/sj.ejcn.1600567.
Howarth NC, Saltzman E, Roberts SB. Dietary fiber and weight regulation. Nutr Rev. 2001 May;59(5):129-39. doi: 10.1111/j.1753-4887.2001.tb07001.x.
Liatis S, Tsapogas P, Chala E, Dimosthenopoulos C, Kyriakopoulos K, Kapantais E, Katsilambros N. The consumption of bread enriched with betaglucan reduces LDL-cholesterol and improves insulin resistance in patients with type 2 diabetes. Diabetes Metab. 2009 Apr;35(2):115-20. doi: 10.1016/j.diabet.2008.09.004. Epub 2009 Feb 20.
Other Identifiers
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QueenMUsz
Identifier Type: -
Identifier Source: org_study_id
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