Adaptive Training Recommendations for Improved Physical Performance
NCT ID: NCT06145152
Last Updated: 2024-03-20
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
PHASE1
40 participants
INTERVENTIONAL
2023-12-05
2025-12-01
Brief Summary
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The training intervention will last for 8 weeks.
Thorough physiological tests will be performed pre and post the training intervention together with muscle biopsies for assessment of mitochondrial function.
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Detailed Description
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The training program will be a mixture of training sessions based on the experience levels of the research subject.
During the onboarding session, data from each persons Garmin watch, will be used to create an optimal training program that takes into account recent training history and which type of training each subject responds the best to. For the subjects in the Adaptive group the training will be adjusted up or down on a daily basis based on subjective readiness, sleep or glucose control. The subjects in the Static group will not get any adjustments in their training program regardless of readiness level.
The length of the training intervention will be 8 weeks.
In addition to adjusting the training for the adaptive group based on daily readiness, the training in that group will be adjusted based on actual training done. For example if a participant fails to reach his suggested heart rate range during a prescribed session, the training load for upcoming sessions will be recalculated so that the weekly overall training load goal is achieved. This kind of adjustments will not be done in the static training group.
Both pre and post the training period a battery of physiological tests will be done including determination of VO2max, lactate threshold and running economy. A performance test (3000m time-trial) will be done on a running track.
A muscle biopsy will be donated from the Vastus Lateralis for assessment of mitochondrial function, efficiency, capacity and density using a combination of methods including respirometry, western blot and enzymatic methods. Capillarization and number of myonuclei will be assessed using histochemical staining. In addition muscle buffering capacity will be investigated using an acid-titration assay.
In addition to the physiological and biochemical investigation, parameters such as subjective training tolerability, perceived pleasure of the training and number of dropouts are important objectives in the proposed studie.
Statistical power calculation. Based on the parallel group design, 80% power, an alpha of 0.05 and a coefficient of variation of 2.4% for VO2max, 4.2% for performance and 14% for mitochondrial function, a differences can be detected between groups of 6%, 11% and 26% for the three outcomes if 15 participants per group are included. 20 subjects will be recruited per group to allow for 5 dropouts per group.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
BASIC_SCIENCE
SINGLE
Study Groups
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Adaptive
Subjects in the Adaptive group will get updated and adjusted training programs based on daily readiness level
Adaptive exercise training
The training recommendation for the day will be adjusted based on the readiness level. The adjustments can be both up or down (increased or decreased training)
Static
Subjects in the Static group will get the same inital training program as the Adaptive group but will not get updated and adjusted training programs based on daily readiness level
Static exercise training
The training recommendation for the day will not be adjusted based on the readiness level.
Interventions
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Adaptive exercise training
The training recommendation for the day will be adjusted based on the readiness level. The adjustments can be both up or down (increased or decreased training)
Static exercise training
The training recommendation for the day will not be adjusted based on the readiness level.
Eligibility Criteria
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Inclusion Criteria
* No chronic diseases
* Able to perform maximal exercise
* Having used a smart watch for training frequently during the last 3 months
* Willing to use wearable technology (Oura ring, continuous glucose monitor, running GPS watch)
Exclusion Criteria
* Recurrent running injuries
* Not willing to use wearable devices
* Performing a subtantial amount of non-running exercise training
18 Years
50 Years
ALL
Yes
Sponsors
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Silicon Valley Exercise Analytics (svexa)
UNKNOWN
The Swedish School of Sport and Health Sciences
OTHER
Responsible Party
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Filip Larsen
Associate Professor
Locations
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Swedish School of Sports and Health Sciences
Stockholm, , Sweden
Countries
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Facility Contacts
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Other Identifiers
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Ellida
Identifier Type: -
Identifier Source: org_study_id
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