Acute Cardiovascular Responses to a Single Exercise Session in Patients With Post-COVID-19 Syndrome

NCT ID: NCT06248151

Last Updated: 2024-12-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

40 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-02-15

Study Completion Date

2025-07-30

Brief Summary

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The objective of the study is to compare the acute cardiorespiratory and perceptual responses to a physical exercise session in those infected by Covid-19 with and without persistent symptoms.

Detailed Description

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The study will be a crossover carried out in two groups (with and without persistent symptoms of Covid-19). Participants in both groups will undergo a control session and an exercise session and cardiorespiratory and perceptual responses will be obtained before, during and after the sessions. In the exercise session, participants will perform aerobic exercises, strength exercises and muscle stretching, while in the control session participants will remain seated. Blood pressure, heart rate, cardiac autonomic modulation, peripheral oxygen saturation, vascular function and perception of affect will be obtained.

Conditions

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Post-Acute COVID-19 Syndrome

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Exercise

In the exercise session, participants will perform aerobic, free active and flexibility exercises and will last approximately 45 minutes.

Group Type EXPERIMENTAL

Exercise session

Intervention Type BEHAVIORAL

Session will included aerobic, resistance and flexibility exercises and will last approximately 45 minutes. The session will begin with aerobic exercises (5 min jumping jacks and 5 min stationary walking). Then, nine strength exercises will be performed for the main muscle groups (3 times of 12 to 15 repetitions, with a 1-minute rest interval) and finally stretching for the main muscle groups

Control session

Intervention Type BEHAVIORAL

Remain seated for 60 min

Control

In the control session, participants will remain seated for 60 minutes.

Group Type OTHER

Exercise session

Intervention Type BEHAVIORAL

Session will included aerobic, resistance and flexibility exercises and will last approximately 45 minutes. The session will begin with aerobic exercises (5 min jumping jacks and 5 min stationary walking). Then, nine strength exercises will be performed for the main muscle groups (3 times of 12 to 15 repetitions, with a 1-minute rest interval) and finally stretching for the main muscle groups

Control session

Intervention Type BEHAVIORAL

Remain seated for 60 min

Interventions

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Exercise session

Session will included aerobic, resistance and flexibility exercises and will last approximately 45 minutes. The session will begin with aerobic exercises (5 min jumping jacks and 5 min stationary walking). Then, nine strength exercises will be performed for the main muscle groups (3 times of 12 to 15 repetitions, with a 1-minute rest interval) and finally stretching for the main muscle groups

Intervention Type BEHAVIORAL

Control session

Remain seated for 60 min

Intervention Type BEHAVIORAL

Other Intervention Names

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Rehabilitation Cardiorespiratory exercises Resistance exercises Flexibility

Eligibility Criteria

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Inclusion Criteria

Post-Covid Syndrome group:

* have had a positive RT-PCR test for Covid-19;
* present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
* have the cognitive and physical capacity to perform the exercises; It is
* low cardiovascular risk classification according to the American College of Sports Medicine criteria.

Healthy group:

* not present persistent symptoms of Post Covid 19 syndrome, which have no other health explanation according to the criteria of the World Health Organization (WHO);
* have the cognitive and physical capacity to perform the exercises; It is
* low cardiovascular risk classification according to the American College of Sports Medicine criteria.
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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University of Nove de Julho

OTHER

Sponsor Role lead

Responsible Party

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Raphael Mendes Ritti Dias

Full Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Raphael Dias, PhD

Role: STUDY_CHAIR

University of Nove de Julho

Locations

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Universidade Nove de Julho

São Paulo, , Brazil

Site Status RECRUITING

Countries

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Brazil

Central Contacts

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Raphael Dias, PhD

Role: CONTACT

+5519999406878

Marilia Correia, PhD

Role: CONTACT

+5511999711669

Facility Contacts

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Raphael Dias

Role: primary

Other Identifiers

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0057/2022

Identifier Type: OTHER

Identifier Source: secondary_id

Acute_Covid

Identifier Type: -

Identifier Source: org_study_id