Inducible Displacements of the Sacroiliac Joint Measured With CTMA

NCT ID: NCT06065644

Last Updated: 2023-10-04

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-01-01

Study Completion Date

2024-08-01

Brief Summary

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To evaluate the influence of different surgical treatment options for kyphoscoliosis we measure the movement of the SI joint with Radiostereometric analysis (RSA) after lumbar fixation with CT motion analysis (CTMA).

Detailed Description

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CTMA is a high precision in vivo measuring method for motion. We intend to measure sacroiliac joint (SIJ) movement in long fixations compared to short fixations. The Center for Implant and Radiostereometric Research Oslo (CIRRO) has extensive experience with RSA and established state of the art measuring method of movement in the SIJ. We have compared the methode with CTMA and established a methode for CTMA measurements at CIRRO. We will measure the movement in the SIJ in patients that have long fixations of 3 or more segments down to S1 and compare it to one segment fixation in the level of L4/5. Null hypothesis

* The SI movement will not increase because of long fixation down to sacrum, the SIJ will not work as an adjacent level and not compensatory increase the movement.
* The increased movement will not result in low back pain and /or pseudo radicular pain to the lower limbs CTMA is a high accuracy measuring method comparable to RSA. With a precision of RSA of 1 degree for rotation we need 10 patients in each group to detect a difference of 2 degrees for power of 90% on an alpha = 99% confidence level. Taking drop-outs into account we need a group size of 15 resulting in 30 patients (Two- sided T-test).

Conditions

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Sacroiliac Joint Unstable

Study Design

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Allocation Method

NON_RANDOMIZED

Intervention Model

PARALLEL

15 patients with long fixation and 15 with fixation of L4/5.
Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Long fixation

CT in a neutral and then by provocation (anterior straight leg raise and figure-of-four).

Group Type EXPERIMENTAL

CTMA

Intervention Type DEVICE

Induced displacement of the Sacroiliac joint

One segment fixation

CT in a neutral and then by provocation (anterior straight leg raise and figure-of-four).

Group Type ACTIVE_COMPARATOR

CTMA

Intervention Type DEVICE

Induced displacement of the Sacroiliac joint

Interventions

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CTMA

Induced displacement of the Sacroiliac joint

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* Long fixations of 3 or more segments down to S1, (also including not correction surgery patients).
* One segment fixations in the level of L4/5 regardless of olisthesis.

Exclusion Criteria

* Medical conditions that affect the SI joint (Sacroileitis, Ankylosing spondylitis, psoriasis, autoimmune illness)
* Do not want to participate and not able to answer PROMs
Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Oslo University Hospital

OTHER

Sponsor Role collaborator

University of Bergen

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Stephan M. Röhrl, PhD

Role: STUDY_DIRECTOR

Oslo University Hospital

Locations

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Ullevål University Hospital

Oslo, , Norway

Site Status

Countries

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Norway

Central Contacts

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Vinjar Brenna Hansen, MD

Role: CONTACT

Stephan M. Röhrl, PhD

Role: CONTACT

References

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Reference Type BACKGROUND
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Nabhan A, Al-Yhary A, Ishak B, Steudel WI, Kollmar O, Steimer O. Analysis of spinal kinematics following implantation of lumbar spine disc prostheses versus fusion: radiological study. J Long Term Eff Med Implants. 2007;17(3):207-16. doi: 10.1615/jlongtermeffmedimplants.v17.i3.40.

Reference Type BACKGROUND
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Sturesson B, Uden A, Vleeming A. A radiostereometric analysis of the movements of the sacroiliac joints in the reciprocal straddle position. Spine (Phila Pa 1976). 2000 Jan 15;25(2):214-7. doi: 10.1097/00007632-200001150-00012.

Reference Type BACKGROUND
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Reference Type BACKGROUND
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Reference Type BACKGROUND
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Broden C, Olivecrona H, Maguire GQ Jr, Noz ME, Zeleznik MP, Skoldenberg O. Accuracy and Precision of Three-Dimensional Low Dose CT Compared to Standard RSA in Acetabular Cups: An Experimental Study. Biomed Res Int. 2016;2016:5909741. doi: 10.1155/2016/5909741. Epub 2016 Jul 10.

Reference Type BACKGROUND
PMID: 27478832 (View on PubMed)

Broden C, Sandberg O, Skoldenberg O, Stigbrand H, Hanni M, Giles JW, Emery R, Lazarinis S, Nystrom A, Olivecrona H. Low-dose CT-based implant motion analysis is a precise tool for early migration measurements of hip cups: a clinical study of 24 patients. Acta Orthop. 2020 Jun;91(3):260-265. doi: 10.1080/17453674.2020.1725345. Epub 2020 Feb 14.

Reference Type BACKGROUND
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Reference Type BACKGROUND
PMID: 25978076 (View on PubMed)

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Reference Type BACKGROUND
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Svedmark P, Berg S, Noz ME, Maguire GQ Jr, Zeleznik MP, Weidenhielm L, Nemeth G, Olivecrona H. A New CT Method for Assessing 3D Movements in Lumbar Facet Joints and Vertebrae in Patients before and after TDR. Biomed Res Int. 2015;2015:260703. doi: 10.1155/2015/260703. Epub 2015 Oct 26.

Reference Type BACKGROUND
PMID: 26587533 (View on PubMed)

Svedmark P, Tullberg T, Noz ME, Maguire GQ Jr, Zeleznik MP, Weidenhielm L, Nemeth G, Olivecrona H. Three-dimensional movements of the lumbar spine facet joints and segmental movements: in vivo examinations of normal subjects with a new non-invasive method. Eur Spine J. 2012 Apr;21(4):599-605. doi: 10.1007/s00586-011-1988-y. Epub 2011 Sep 1.

Reference Type BACKGROUND
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Eriksson T, Maguire GQ Jr, Noz ME, Zeleznik MP, Olivecrona H, Shalabi A, Hanni M. Are low-dose CT scans a satisfactory substitute for stereoradiographs for migration studies? A preclinical test of low-dose CT scanning protocols and their application in a pilot patient. Acta Radiol. 2019 Dec;60(12):1643-1652. doi: 10.1177/0284185119844166. Epub 2019 May 1. No abstract available.

Reference Type BACKGROUND
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Kibsgard TJ, Rohrl SM, Roise O, Sturesson B, Stuge B. Movement of the sacroiliac joint during the Active Straight Leg Raise test in patients with long-lasting severe sacroiliac joint pain. Clin Biomech (Bristol). 2017 Aug;47:40-45. doi: 10.1016/j.clinbiomech.2017.05.014. Epub 2017 May 29.

Reference Type BACKGROUND
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Kibsgard TJ, Roise O, Stuge B, Rohrl SM. Precision and accuracy measurement of radiostereometric analysis applied to movement of the sacroiliac joint. Clin Orthop Relat Res. 2012 Nov;470(11):3187-94. doi: 10.1007/s11999-012-2413-5. Epub 2012 Jun 14.

Reference Type BACKGROUND
PMID: 22695864 (View on PubMed)

Other Identifiers

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IDSCT

Identifier Type: -

Identifier Source: org_study_id

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