Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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COMPLETED
NA
45 participants
INTERVENTIONAL
2023-08-01
2023-09-30
Brief Summary
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45 systemically healthy participants were enrolled in this investigation, equally subdivided into three groups of 15 patients each: gingivitis, periodontitis (stage III) and control group with healthy gingiva. Probing depth, clinical attachment level, gingival and plaque index were registered. GCF levels of galectin-1 and -3 were evaluated in all included groups (before and after non-surgical treatment for periodontitis group) using enzyme linked immune-sorbent assay (ELISA) kit.
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Detailed Description
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Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
DIAGNOSTIC
SINGLE
Study Groups
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Group I
patients diagnosed with gingivitis
GCF sample collection
collecting GCF from deepest sites by paper points
Group II
patients diagnosed with periodontitis
GCF sample collection
collecting GCF from deepest sites by paper points
non-surgical periodontal treatment
performing scaling and root planning using ultrasonic device and manual curettes
Group III
healthy control
GCF sample collection
collecting GCF from deepest sites by paper points
Interventions
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GCF sample collection
collecting GCF from deepest sites by paper points
non-surgical periodontal treatment
performing scaling and root planning using ultrasonic device and manual curettes
Eligibility Criteria
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Inclusion Criteria
2. Not suffering from systemic diseases, pregnancy/lactation.
3. Not taking contraceptive pills, antibiotics, anti-inflammatory, or immunosuppressive drugs before inclusion in the study by 6 months.
4. Patients with only gingivitis or periodontitis stage III.
5. Periodontitis patients who did not receive any professional periodontal treatment in the last 6 months.
Exclusion Criteria
2. having systemic diseases, pregnancy/lactation.
3. taking contraceptive pills, antibiotics, anti-inflammatory, or immunosuppressive drugs in the past 6 months.
4. Patients having periodontitis any other stage than stage III.
5. Periodontitis patients who receive any professional periodontal treatment in the last 6 months.
25 Years
60 Years
ALL
Yes
Sponsors
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Fayoum University
OTHER
Responsible Party
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Nayroz Tarrad
associate professor
Locations
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faculty of dentistry, Fayoum university
Al Fayyum, , Egypt
Countries
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References
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Tarrad NAF, Shaker OG, Elbanna RMH, AbdelKawy M. "Outcome of non-surgical periodontal treatment on Gal-1 and Gal-3 GCF levels in periodontitis patients: a case-control study". Clin Oral Investig. 2024 May 14;28(6):309. doi: 10.1007/s00784-024-05688-1.
Other Identifiers
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REC-FDBSU/03082023-1/AM
Identifier Type: -
Identifier Source: org_study_id
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