An Observational Study of Local Relapse After High Grade Osteosarcoma

NCT ID: NCT06017518

Last Updated: 2025-09-22

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-13

Study Completion Date

2026-06-30

Brief Summary

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multicenter retrospective and prospective study in patients with high-grade osteosarcoma

Detailed Description

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This is a multicenter retrospective and prospective study that will analyze all cases with of diagnosis of local relapse in high-grade osteosarcoma from 01 January 1980 and all new cases referring to each participant site.

Conditions

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Osteosarcoma

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

CROSS_SECTIONAL

Eligibility Criteria

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Inclusion Criteria

* Patients who experienced LR as first event of recurrence after treatment for localized high-grade osteosarcoma of bone, including cases with synchronous lung metastases
* Adequate patient compliance to follow-up visits
* Written informed consent prior to any study-specific analysis and/or data collection
* No age limits

Exclusion Criteria

* Cases of LR demonstrated after \> 3 months after metastatic disease
* Impossibility to ensure adequate compliance
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Istituto Ortopedico Rizzoli

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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IRCCS Istituto Ortopedico Rizzoli

Bologna, BO, Italy

Site Status RECRUITING

Azienda Ospedaliero-Universitaria Pisana

Pisa, PI, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Emanuela Palmerini, MD

Role: CONTACT

051/6366 ext. 668

Facility Contacts

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Emanuela Palmerini, MD

Role: primary

051/6366 ext. 668

Luca Coccoli, MD

Role: primary

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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OSTEO LR

Identifier Type: -

Identifier Source: org_study_id

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