Patterns of Care and Outcomes in METAstatic Soft Tissue SARComa

NCT ID: NCT03977818

Last Updated: 2025-09-05

Study Results

Results available

Outcome measurements, participant flow, baseline characteristics, and adverse events have been published for this study.

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Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

2165 participants

Study Classification

OBSERVATIONAL

Study Start Date

1990-01-01

Study Completion Date

2017-01-01

Brief Summary

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Well-designed observational studies of individuals with rare tumors are needed to improve patient care, clinical investigations, and the education of healthcare professionals.

The patterns of care, outcomes, and prognostic factors of a cohort of 2225 patients with metastatic soft tissue sarcomas who were diagnosed between 1990 and 2013 and documented in the prospectively maintained database of the French Sarcoma Group will be analyzed with a focus on : number/frequency of systemic treatments per patient, number/frequency of patients with locoregional treatment of the metastasis, number/frequency of patients with chemotherapy, number/frequency of patients with an off-label drug.

Outcome (time-to-next treatment \[TNT\] and overall survival \[OS\]) will be reported according to histological subtype, as well as the association between TNT and OS.

Prognostic factors of OS will be investigated.

Detailed Description

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Conditions

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Sarcoma Metastases Chemotherapy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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patients with metastatic softtissue sarcomas diagnosed between 1990 and 2013

No interventions assigned to this group

Eligibility Criteria

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Inclusion Criteria

* advanced soft tissue sarcoma
* age \> 18

Exclusion Criteria

\-
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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French Sarcoma Group

OTHER

Sponsor Role collaborator

Institut Bergonié

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Antoine Italiano, MD/PhD

Role: PRINCIPAL_INVESTIGATOR

Institut Bergonié, Comprehensive Cancer Center

Locations

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Institut Bergonié, Comprehensive Cancer Center

Bordeaux, , France

Site Status

Centre Léon Bérard, Comprehensive Cancer Center

Lyon, , France

Site Status

Institut Gustave Roussy, Comprehensive Cancer Center

Villejuif, , France

Site Status

Countries

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France

References

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Savina M, Le Cesne A, Blay JY, Ray-Coquard I, Mir O, Toulmonde M, Cousin S, Terrier P, Ranchere-Vince D, Meeus P, Stoeckle E, Honore C, Sargos P, Sunyach MP, Le Pechoux C, Giraud A, Bellera C, Le Loarer F, Italiano A. Patterns of care and outcomes of patients with METAstatic soft tissue SARComa in a real-life setting: the METASARC observational study. BMC Med. 2017 Apr 10;15(1):78. doi: 10.1186/s12916-017-0831-7.

Reference Type RESULT
PMID: 28391775 (View on PubMed)

Other Identifiers

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IB2017-METASARC

Identifier Type: -

Identifier Source: org_study_id

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