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A French Multicenter Observational Retrospective Study of Rare Primary Liver Cancers

NCT ID: NCT06541652

Last Updated: 2025-08-05

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

150 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-03-26

Study Completion Date

2031-02-28

Brief Summary

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The aim of this French multicenter retrospective study is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences. This retrospective cohort will be the backbone of future translational studies aimed at identifying new molecular, histological, circulating and radiological tumor biomarkers, potentially useful at every stage of diagnosis and prognostic or theranostic evaluation.

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Detailed Description

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The aim is to describ rare primary hepatic cancers clinical, histological and radiological features, to obtain a biological tumor and blood collection, and to evaluate the efficacy of treatments received in clinical practice in order to determine optimal therapeutic sequences.

Conditions

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Hepatocholangiocarcinoma Fibrolamellar Carcinoma Hepatic Epithelioid Hemangioendothelioma Hepatoblastoma Hepatic Neuroendocrine Carcinoma Hepatic Carcinosarcomas Hepatic Cystadenoma Hepatic Leiomyosarcomas Hepatic Angiosarcomas Cholangiocarcinoma

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Eligibility Criteria

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Inclusion Criteria

* 18 years of age or older,
* with histologically proven hepato-cholangiocarcinoma, fibrolamellar hepatocellular carcinoma, epithelioid hemangioendothelioma or hepatic angiosarcoma
* diagnosed after January 01, 2018 living or deceased at the time of registration in the cohort
* for living patients who have not objected to the research: (note of non-objection to be attached° agreeing to participate in ancillary studies must sign the biological consent form for participation in biological studies.

Exclusion Criteria

* without social security
* No access to tumor block
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Société Nationale Française de Gastroentérologie

OTHER

Sponsor Role collaborator

Federation Francophone de Cancerologie Digestive

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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jean-charles nault, Pr

Role: PRINCIPAL_INVESTIGATOR

Federation Francophone de Cancerologie Digestive

Locations

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CHU Amiens picardie

Amiens, , France

Site Status RECRUITING

Chu Angers

Angers, , France

Site Status RECRUITING

Ch - Centresimone Veil de Beauvais

Beauvais, , France

Site Status RECRUITING

Chu Jean Minjoz

Besançon, , France

Site Status NOT_YET_RECRUITING

Ch Bethune Beuvry

Béthune, , France

Site Status NOT_YET_RECRUITING

Avicenne

Bobigny, , France

Site Status RECRUITING

Cote de Nacre

Caen, , France

Site Status NOT_YET_RECRUITING

Centre Hospitalier

Calais, , France

Site Status RECRUITING

Chu de Clichy Hopital Beaujon

Clichy, , France

Site Status RECRUITING

Centre Hospitalier Universitaire Henri Mondor

Créteil, , France

Site Status RECRUITING

CHU

Dijon, , France

Site Status RECRUITING

Chu Grenobles Alpes

La Tronche, , France

Site Status RECRUITING

Centre Hospital Universitaire de lille

Lille, , France

Site Status RECRUITING

Longjumeau Ch Nord Essone

Longjumeau, , France

Site Status RECRUITING

Ch Edouard Herriot

Lyon, , France

Site Status RECRUITING

Centre Léon Berard

Lyon, , France

Site Status RECRUITING

La Clinique de La Sauvegarde

Lyon, , France

Site Status RECRUITING

Chu Edouard Herriot

Lyon, , France

Site Status RECRUITING

Lyon Cac Leon Berard

Lyon, , France

Site Status RECRUITING

Lyon La Croix Rousse

Lyon, , France

Site Status NOT_YET_RECRUITING

Hopital Saint Joseph

Marseille, , France

Site Status RECRUITING

Chu de La Timone

Marseille, , France

Site Status RECRUITING

CHR - Metz Thionville Hopital de Mercy

Metz, , France

Site Status RECRUITING

CHU La Source

Orléans, , France

Site Status NOT_YET_RECRUITING

Chu de Paris Saint Antoine

Paris, , France

Site Status RECRUITING

AP - HP - Pitié Salpêtrière

Paris, , France

Site Status RECRUITING

PAU CH

Pau, , France

Site Status NOT_YET_RECRUITING

Centre Hospitalier de Perpignan

Perpignan, , France

Site Status RECRUITING

Hopital Haut Leveque

Pessac, , France

Site Status RECRUITING

Chu de Poitiers

Poitiers, , France

Site Status RECRUITING

CH - Annecy Genevois

Pringy, , France

Site Status RECRUITING

Chu Robert Debre

Reims, , France

Site Status RECRUITING

CAC - Eugène Marquis

Rennes, , France

Site Status NOT_YET_RECRUITING

Ico Site Rene Gauducheau

Saint-Herblain, , France

Site Status NOT_YET_RECRUITING

Hopital Nord Chu Saint Etienne

Saint-Priest-en-Jarez, , France

Site Status RECRUITING

Groupe Hospitalier Rance Emeraude

St-Malo, , France

Site Status RECRUITING

Chu Rangueil

Toulouse, , France

Site Status RECRUITING

Chru de Tours

Tours, , France

Site Status NOT_YET_RECRUITING

Chu Paul Brousse

Villejuif, , France

Site Status NOT_YET_RECRUITING

Gustave Roussy

Villejuif, , France

Site Status NOT_YET_RECRUITING

Countries

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France

Central Contacts

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lila gaba

Role: CONTACT

[email protected]
06 99 78 84 73

Facility Contacts

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eric NGUYEN KHAC, MD

Role: primary

[email protected]
03 22 66 89 47

FREDERIC OBERTI, MD

Role: primary

[email protected]
02 41 35 53 80

HANIFA AMMARGUELLAT, MD

Role: primary

[email protected]
03 44 11 21 22

Angelique VIENOT

Role: primary

[email protected]
03 81 66 83 41

Helene VAN DAMME, MD

Role: primary

[email protected]
03 21 64 43 19

JEAN CHARLES NAULT, PR

Role: primary

[email protected]
0148024149

Isabelle OLLIVIER HOURMAND

Role: primary

[email protected]
02 31 06 45 44

Nathalie IBRAHIM

Role: primary

[email protected]
0321463431

MOHAMED BOUATTOUR, MD

Role: primary

[email protected]
01.40.87.54.87

HELENE REGNAULT, MD

Role: primary

[email protected]
01 98 12 13 52

MARIANNE LATOURNERIE, MD

Role: primary

[email protected]
03 80 29 37 50

BLEUENN BRUSSET, MD

Role: primary

[email protected]
04 76 76 66 87

Emmanuel Boleslawski, pr

Role: primary

[email protected]
0320446364

Manal AWAD, MD

Role: primary

[email protected]
01 64 54 29 41

JEROME DUMORTIER, MD

Role: primary

[email protected]
04 72 11 01 47

aurelien dupre

Role: primary

[email protected]
0478782933

BENJAMIN DARNIS, MD

Role: primary

[email protected]
04 37 49 70 10

Jérôme DUMORTIER

Role: primary

[email protected]
04 72 11 01 11

Aurelien DUPRE

Role: primary

[email protected]
04 78 78 27 51

Philippe MERLE

Role: primary

[email protected]
04 26 10 93 56

XAVIER ADHOUTE, MD

Role: primary

[email protected]
04 91 80 82 12

RENE GEROLAMI, MD

Role: primary

[email protected]
04 91 38 36 96

Guillaume CONROY

Role: primary

[email protected]
03 87 55 33 05

Barbara DAUVOIS

Role: primary

[email protected]
02 38 51 47 04

MARIE LEQUOY, MD

Role: primary

[email protected]
01 49 28 31 54

MANON ALLAIRE, MD

Role: primary

[email protected]
01 42 16 10 34

JULIETTE THAURY

Role: primary

[email protected]
0559724983

Faiza Khemissa-Akouz, PhD

Role: primary

[email protected]
33-4-6861-6751

JEAN FREDERIC BLANC, PR

Role: primary

[email protected]
05 56 79 58 06

DAVID TOUGERON, PR

Role: primary

[email protected]
05 49 44 38 35

Emmanuel Maillard, md

Role: primary

[email protected]
04 50 63 66 05

ELIA GIGANTE, MD

Role: primary

[email protected]
0326789219

JULIEN EDELINE, MD

Role: primary

[email protected]
02 99 25 31 96

TIMOTHEE VIGNAUD, DR

Role: primary

[email protected]
0240679984

Jean-Marc PHELIP, Pr

Role: primary

[email protected]
04 77 82 86 19

VIAUD JULIETTE, Dr

Role: primary

[email protected]
02 99 21 29 80

Jean-Marie PERON, Pr

Role: primary

[email protected]
05 61 77 94 83

ANAIS JAILLAIS, MD

Role: primary

[email protected]
02 47 47 47 47

Olivier ROSMORDUC

Role: primary

[email protected]

Alice BOILEVE, Dr

Role: primary

[email protected]
0142112202

Other Identifiers

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2023-A01517-38

Identifier Type: REGISTRY

Identifier Source: secondary_id

CAPRIH COHORT

Identifier Type: -

Identifier Source: org_study_id

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