Living Donor Liver Transplant for Unresectable Colorectal Liver Metastases
NCT ID: NCT05248581
Last Updated: 2025-07-08
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
25 participants
OBSERVATIONAL
2019-08-16
2027-08-01
Brief Summary
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Detailed Description
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Our primary outcome of interest was the OS and recurrence-free survival (RFS) of patients who underwent LDLT at our center.
Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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All Participants
Potential subjects for this registry must have Stage IV colorectal cancer with liver metastases and be candidates for liver transplantation based on multidisciplinary discussion by the Liver transplantation team. Patients must demonstrate favorable tumor biology and no evidence of extra hepatic disease.
Liver transplantation
living donor liver transplantation
Interventions
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Liver transplantation
living donor liver transplantation
Eligibility Criteria
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Inclusion Criteria
* Non-amenable to curative hepatic resection as defined by FLR \<30%
* Histologically confirmed adenocarcinoma of the colon or rectum
* Candidate for LDLT for colorectal liver metastasis per the University of Rochester liver transplant program
Exclusion Criteria
* Unwilling to consent
18 Years
ALL
No
Sponsors
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University of Rochester
OTHER
Responsible Party
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Roberto Hernandez-Alejandro
Professor
Principal Investigators
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Roberto Hernandez-Alejandro, MD
Role: PRINCIPAL_INVESTIGATOR
University of Rochester
Matthew Byrne, MD
Role: STUDY_DIRECTOR
University of Rochester
Locations
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University of Rochester Medical Center
Rochester, New York, United States
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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STUDY00004076
Identifier Type: -
Identifier Source: org_study_id
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