Status of Surgical Resection and Histologic Subtype as Predictors of Local Recurrence in Retroperitoneal Liposarcoma

NCT ID: NCT05428579

Last Updated: 2022-06-23

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

60 participants

Study Classification

OBSERVATIONAL

Study Start Date

2017-10-01

Study Completion Date

2018-11-01

Brief Summary

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Soft tissue sarcomas are rare malignant tumors. Liposarcoma constitute the most frequent histological subtype of retroperitoneal sarcoma. The prognosis of soft tissue sarcomas depend on clinical and histologic characteristics. Objective: Evaluate variables that may be related to overall survival and local recurrence free survival in patients with retroperitoneal liposarcoma. Methods: retrospective analysis of medical records of 60 patients attended from 1997 to 2017, who underwent surgical resection of retroperitoneal liposarcoma.

Detailed Description

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Conditions

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Liposarcoma of Soft Tissue Surgical Procedure, Unspecified

Study Design

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Observational Model Type

CASE_ONLY

Study Time Perspective

RETROSPECTIVE

Interventions

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Retroperitoneal Liposarcoma resection

Retroperitoneal Liposarcoma resection

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* All patients who underwent surgical resection of retroperitoneal liposarcoma

Exclusion Criteria

* Unresectable disease (upper mesenteric artery or vein involvement) or metastatic disease (sarcomatosis or distant disease)
Minimum Eligible Age

17 Years

Maximum Eligible Age

76 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Sao Paulo General Hospital

OTHER

Sponsor Role lead

Responsible Party

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Edivaldo Massazo Utiyama

Full Professor of III General Surgery Division

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Hospital das Clínicas da Faculdade de Medicina da Universidade de São Paulo

São Paulo, , Brazil

Site Status

Countries

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Brazil

References

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Neuhaus SJ, Barry P, Clark MA, Hayes AJ, Fisher C, Thomas JM. Surgical management of primary and recurrent retroperitoneal liposarcoma. Br J Surg. 2005 Feb;92(2):246-52. doi: 10.1002/bjs.4802.

Reference Type RESULT
PMID: 15505870 (View on PubMed)

Singer S, Antonescu CR, Riedel E, Brennan MF. Histologic subtype and margin of resection predict pattern of recurrence and survival for retroperitoneal liposarcoma. Ann Surg. 2003 Sep;238(3):358-70; discussion 370-1. doi: 10.1097/01.sla.0000086542.11899.38.

Reference Type RESULT
PMID: 14501502 (View on PubMed)

Other Identifiers

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29071984

Identifier Type: -

Identifier Source: org_study_id

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