Combined HCC-MFCCC

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

100 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-01-01

Study Completion Date

2017-05-15

Brief Summary

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Combined hepatocellular and mass-forming cholangiocarcinoma (cHCC-MFCCC) is a rare tumor. The aim of this study was the analysis of the outcome comparing such tumor with classic hepatocellular carcinoma (HCC) and mass-forming cholangiocarcinoma (MFCCC).

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Detailed Description

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The institutional prospectively maintained database was queried, and 20 patients with cHCC-MFCCC were identified. A 2:1 match was performed with 40 patients operated in the same period for HCC, and with 40 operated for MFCCC. Only T1 or T2 patients N0 M0 were considered. Primary endpoint was the overall survival (OS) and disease-free survival (DFS).

Conditions

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Liver Carcinoma Hepatocellular Carcinoma Cholangiocarcinoma Surgery

Study Design

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Observational Model Type

CASE_CONTROL

Study Time Perspective

RETROSPECTIVE

Study Groups

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cHCC-MFCCC

Patients affected by combined HCC-MFCCC

Hepatectomy

Intervention Type PROCEDURE

Removal of a part of the liver

HCC

Patients affected by classical HCC

Hepatectomy

Intervention Type PROCEDURE

Removal of a part of the liver

MFCCC

Patients affected by classical MFCCC

Hepatectomy

Intervention Type PROCEDURE

Removal of a part of the liver

Interventions

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Hepatectomy

Removal of a part of the liver

Intervention Type PROCEDURE

Other Intervention Names

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Liver resection Liver surgery

Eligibility Criteria

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Inclusion Criteria

* positive histology for cHCC-MFCCC, HCC, and MFCCC
* complete clinical, surgical, pathological and follow-up data.

Exclusion Criteria

* patients preoperatively treated with chemotherapy, radiofrequency ablation or trans-arterial therapies were excluded.
* patients operated for recurrent disease and/or with non-radical surgery
* patients with missing data were also excluded

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No