Perioperative Outcomes of Simultaneous Colorectal and Liver Resections

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

766 participants

Study Classification

OBSERVATIONAL

Study Start Date

2022-06-30

Study Completion Date

2022-07-22

Brief Summary

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The use of a simultaneous resection in patients with synchronous colorectal liver metastases has increased over the past decades. However, it remains unclear when a simultaneous resection is beneficial and when it should be avoided. The objective of this retrospective study is therefore to compare the outcomes of a simultaneous resection for synchronous colorectal liver metastases in different settings, and to assess which factors are independently associated with unfavorable outcomes.

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Detailed Description

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Conditions

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Colorectal Cancer Metastatic Surgical Procedure, Unspecified

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Minor liver resection

Minor liver resection (\<3 contiguous segments) in the anterolateral segments

No interventions assigned to this group

Technically major liver resection

Minor liver resection (\<3 contiguous segments) in the posterosuperior segments (Segment 1,4a,7,8)

Technically major liver resection

Intervention Type PROCEDURE

Minor liver resection (\<3 contiguous segments) in the posterosuperior segments (segment 1,4a,7,8)

Major liver resection

Major liver resection (3 or more contiguous segments)

Major liver resection

Intervention Type PROCEDURE

Major liver resection (3 or more contiguous segments)

Interventions

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Major liver resection

Major liver resection (3 or more contiguous segments)

Intervention Type PROCEDURE

Technically major liver resection

Minor liver resection (\<3 contiguous segments) in the posterosuperior segments (segment 1,4a,7,8)

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* Elective minimally invasive or open simultaneous resection of colorectal cancer and synchronous colorectal liver metastases

Exclusion Criteria

* (Partially) robotic-assisted or thoracoscopic procedures
* First stage of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS)
* Patients that underwent major concurrent procedures

Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No