Chemotherapy and Tumor Clearance in Hepatic Resections for Colorectal Liver Metastases.

NCT ID: NCT05273489

Last Updated: 2022-03-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Total Enrollment

170 participants

Study Classification

OBSERVATIONAL

Study Start Date

2004-01-01

Study Completion Date

2021-10-31

Brief Summary

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Retrospective analysis of a prospectively collected database of 170 patients between 2004 and 2020, who underwent liver resections for CRLM (colorectal liver metastases) at The Queen Elizabeth Hospital trying to determine rates and patterns of recurrence following liver resections for CRLM and concurrently, characterise clinical, pathological and treatment-related factors that could function as predictors of recurrence or survival, particularly neoadjuvant chemotherapy and tumour clearance.

Detailed Description

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This is a descriptive, observational study with retrospective analysis of a prospectively collated database. This database included all patients who underwent curative hepatic resections for CRLM (colorectal liver metastases) at The Queen Elizabeth Hospital (Adelaide, Australia) between December 2004 and October 2020.

Conditions

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Colorectal Cancer Metastatic Liver Metastases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

OTHER

Interventions

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Hepatectomy

Neoadjuvant treatment

Intervention Type PROCEDURE

Other Intervention Names

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Chemotherapy

Eligibility Criteria

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Inclusion Criteria

* Patients who underwent a liver resection for CRLM at The Queen Elizabeth Hospital between December 2004 to September 2020

Exclusion Criteria

* Patients whose procedures were abandoned due to unresectable tumour burden
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Adelaide

OTHER

Sponsor Role collaborator

Hospital Maciel

OTHER

Sponsor Role lead

Responsible Party

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Mauro Andres Perdomo, MD, MHA

MD, General Surgeon

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Mauro A Perdomo, MD, MHA

Role: PRINCIPAL_INVESTIGATOR

Assitant Professor at Clinica Quirurgica 3. Universidad de la Republica. Monteviedo, Uruguay

Provided Documents

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Document Type: Study Protocol

View Document

Other Identifiers

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CRLM1

Identifier Type: -

Identifier Source: org_study_id

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