Fracture Risk Evaluation of Bone Metastases Derived From Carcinoma

NCT ID: NCT06524843

Last Updated: 2025-12-15

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

250 participants

Study Classification

OBSERVATIONAL

Study Start Date

2024-09-23

Study Completion Date

2026-12-31

Brief Summary

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From the archives of the Rizzoli institute all patients (approximately 750) treated for bone metastases from 01/01/2010 to 31/12/2022.

A review will be made from the medical records, radiological imaging, and histological data of these patients

Detailed Description

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Conditions

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Bone Metastases

Study Design

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Observational Model Type

COHORT

Study Time Perspective

RETROSPECTIVE

Study Groups

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Patients

Male and female patients affected by bone metastases derived from carcinoma, treated at Rizzoli Orthopaedic Institute from 01/01/2010 to 31/12/2022

Analysis

Intervention Type OTHER

Analysis and review of imaging and clinical data

Interventions

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Analysis

Analysis and review of imaging and clinical data

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age ≥ 18 years
* Diagnosis of bone metastasis from carcinoma, regardless of the type of carcinoma, and of the number and location of the metastases
* Availability of imaging and clinical data
* Availability of at least one follow-up during the last 12 months form diagnosis

Exclusion Criteria

* At least one inclusion creteria not met
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Costantino Errani

OTHER

Sponsor Role lead

Responsible Party

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Costantino Errani

MD

Responsibility Role SPONSOR_INVESTIGATOR

Locations

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IRCCS Istituto Ortopedico Rizzoli

Bologna, Emilia-Romagna, Italy

Site Status RECRUITING

Countries

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Italy

Central Contacts

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Costantino Errani, MD

Role: CONTACT

0516366 ext. 103

Roberta Laranga, PhD

Role: CONTACT

051636 ext. 5123

Facility Contacts

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Costantino Errani, MD

Role: primary

0516366 ext. 103

Roberta Laranga, PhD

Role: backup

051636 ext. 5123

References

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Mirels H. Metastatic disease in long bones: A proposed scoring system for diagnosing impending pathologic fractures. 1989. Clin Orthop Relat Res. 2003 Oct;(415 Suppl):S4-13. doi: 10.1097/01.blo.0000093045.56370.dd.

Reference Type BACKGROUND
PMID: 14600587 (View on PubMed)

Coleman RE. Clinical features of metastatic bone disease and risk of skeletal morbidity. Clin Cancer Res. 2006 Oct 15;12(20 Pt 2):6243s-6249s. doi: 10.1158/1078-0432.CCR-06-0931.

Reference Type BACKGROUND
PMID: 17062708 (View on PubMed)

Other Identifiers

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FRAIL-RAW

Identifier Type: -

Identifier Source: org_study_id

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