Optimizing Postoperative Pain Control After Laparoscopic Colorectal Surgery

NCT ID: NCT06007378

Last Updated: 2025-07-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

120 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-05

Study Completion Date

2025-07-22

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Erector spinae plane block (ESPB) is a novel regional block technique that was proven to have superior outcomes in relieving postoperative pain in colorectal surgeries.Ketamine enhances the impact of local anaesthetics by reducing the duration and extent of motor block while shortening the onset of sensory and motor block.Transdermal Fentanyl Patch (TFP) was better than transdermal buprenorphine in postoperative analgesia following abdominal surgeries.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Postoperative Pain

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

PREVENTION

Blinding Strategy

DOUBLE

Participants Caregivers

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Bupivacaine and ketamine

Group Type OTHER

Bupivacaine and ketamine

Intervention Type OTHER

Bilateral erector spinae plane block (bupivacaine and ketamine)

Bupivacaine and transdermal fentanyl patch

Group Type OTHER

Bupivacaine and transdermal fentanyl patch

Intervention Type OTHER

Bilateral erector spinae plane block (bupivacaine) and transdermal fentanyl patch

Bupivacaine

Group Type OTHER

Bupivacain

Intervention Type OTHER

Bilateral erector spinae plane block (bupivacaine)

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Bupivacaine and ketamine

Bilateral erector spinae plane block (bupivacaine and ketamine)

Intervention Type OTHER

Bupivacaine and transdermal fentanyl patch

Bilateral erector spinae plane block (bupivacaine) and transdermal fentanyl patch

Intervention Type OTHER

Bupivacain

Bilateral erector spinae plane block (bupivacaine)

Intervention Type OTHER

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Patients undergoing laparoscopic colorectal surgery.
* American Society of Anesthesiologists (ASA) physical status I or II.

Exclusion Criteria

* Known allergy to one of the study medications.
* Skin infections at the site of the needle puncture.
* Hepatic, renal or cardiac dysfunction.
* Patients diagnosed with obstructive sleep apnoea
Minimum Eligible Age

21 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Ain Shams University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Ibrahim Mamdouh Esmat

Assistant Professor of Anesthesia and Intensive Care, Faculty of Medicine, Ain- shams University, Cairo, Egypt.

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Ain-Shams University Hospitals

Cairo, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

FMASU MS 416 / 2023

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Ketamine in Colorectal Surgery
NCT02785003 WITHDRAWN PHASE4
Ketamine vs Hydromorphone
NCT03001843 COMPLETED PHASE4