Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women

NCT ID: NCT06004544

Last Updated: 2023-08-30

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Total Enrollment

10000 participants

Study Classification

OBSERVATIONAL

Study Start Date

2023-02-06

Study Completion Date

2028-12-31

Brief Summary

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Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed. Ejection fraction (EF) was quantified using biplane Simpson's method.

Detailed Description

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Consecutive obstetric patients attending routine antenatal visits were enrolled in this ongoing registry. A standardized 2D transthoracic echocardiogram (TTE) protocol was employed, including parasternal long and short, apical 4- and 2-chamber views. Continuous wave and pulse wave Doppler were used to assess left ventricular outflow tract (LVOT) gradients. Left ventricular (LV) function was quantified using biplane Simpson's method and visually assessed by two independent readers. Patients with significant valve disease or congenital heart disease underwent complete TTE. Those diagnosed with LV dysfunction or other cardiovascular diseases (CVD) were referred to the Cardio-Obstetrics clinic for further management and long-term follow-up.

Conditions

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Cardiovascular Diseases in Pregnancy

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* Obstetric patients attending routine antenatal visits

Exclusion Criteria

* Patients refused to give consent for echocardiography or participation in the study
Eligible Sex

FEMALE

Accepts Healthy Volunteers

No

Sponsors

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Jinnah Postgraduate Medical Centre

OTHER_GOV

Sponsor Role collaborator

National Institute of Cardiovascular Diseases, Pakistan

OTHER

Sponsor Role lead

Responsible Party

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Sabha Bhatti

Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Sabha Bhatti, MD

Role: PRINCIPAL_INVESTIGATOR

National Institute of Cardiovascular Diseases

Locations

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National Institute of Cardiovascular Diseases (NICVD)

Karachi, Sindh, Pakistan

Site Status RECRUITING

Countries

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Pakistan

Central Contacts

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Sabha Bhatti, MD

Role: CONTACT

+92 335 5554346

Shakeela Naz, FCPS

Role: CONTACT

+92 331 3596502

References

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Bhatti S, Naz S, Gurmani S, Yasmin H, Atif U, Karim M, Ahmed S, Zehra K, Hakeem A, Qamar N. Prospective Pakistan Registry of Echocardiographic Screening in Asymptomatic Pregnant Women. JACC Adv. 2024 Sep 2;3(12):101215. doi: 10.1016/j.jacadv.2024.101215. eCollection 2024 Dec.

Reference Type DERIVED
PMID: 39817089 (View on PubMed)

Other Identifiers

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IRB-33/2023

Identifier Type: -

Identifier Source: org_study_id

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