Correlation of Right Atrial Strain With Pulmonary Hypertension, Right Ventricular Function And Outcome In Pediatric Patients
NCT ID: NCT05699681
Last Updated: 2023-01-26
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
50 participants
OBSERVATIONAL
2021-01-01
2023-02-15
Brief Summary
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Detailed Description
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Conditions
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Study Design
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COHORT
PROSPECTIVE
Study Groups
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Study cohort
Children aged below 12 years undergoing elective cardiac surgery for congenital heart disease with left to right shunt with prior evidence of pulmonary arterial hypertension on preoperative echocardiography
Transthoracic and transesophageal echocardiography
After induction of anaesthesia and stabilization of hemodynamics, transthoracic echocardiography will be done on a GE Vivid e9 workstation (GE Vingmed, Horton, Norway) with MS5 transthoracic probe with synchronized ECG.
From TTE the following views and measurements will be acquired :
* Apical four chamber (A4C) view
* Apical two chamber view (A2C) view
* Right ventricle (RV) focused A4C view
* Right ventricular systolic pressure (RVSP)
* Pulmonary arterial acceleration time (PAAT),
* Tricuspid annular plane systolic excursion (TAPSE),
* Tricuspid annular plane systolic velocity (s'),
* Right ventricular fractional area change (RV FAC)
* RV free wall strain,
* RV myocardial performance index (MPI),
* RV isovolumic relaxation time (IVRT),
* RV isovolumic acceleration time (IVA)
Invasive PA pressure measurement will be done after surgical exposure with a fine needle and a zeroed transducer by the Surgeon.
Interventions
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Transthoracic and transesophageal echocardiography
After induction of anaesthesia and stabilization of hemodynamics, transthoracic echocardiography will be done on a GE Vivid e9 workstation (GE Vingmed, Horton, Norway) with MS5 transthoracic probe with synchronized ECG.
From TTE the following views and measurements will be acquired :
* Apical four chamber (A4C) view
* Apical two chamber view (A2C) view
* Right ventricle (RV) focused A4C view
* Right ventricular systolic pressure (RVSP)
* Pulmonary arterial acceleration time (PAAT),
* Tricuspid annular plane systolic excursion (TAPSE),
* Tricuspid annular plane systolic velocity (s'),
* Right ventricular fractional area change (RV FAC)
* RV free wall strain,
* RV myocardial performance index (MPI),
* RV isovolumic relaxation time (IVRT),
* RV isovolumic acceleration time (IVA)
Invasive PA pressure measurement will be done after surgical exposure with a fine needle and a zeroed transducer by the Surgeon.
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Prior evidence of pulmonary arterial hypertension on preoperative echocardiography.
Exclusion Criteria
* Children with history of previous cardiac surgery,
* Hemodynamic instability
* Non-sinus rhythm
1 Month
12 Years
ALL
No
Sponsors
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Post Graduate Institute of Medical Education and Research, Chandigarh
OTHER
Responsible Party
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Dr. Subhrashis Guha Niyogi
Principal Investigator, Division of Cardiac Anaesthesia, Department of Anaesthesia and Intensive Care
Locations
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Postgraduate Institute of Medical Education & Research
Chandigarh, , India
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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NK/6412/Study/494
Identifier Type: -
Identifier Source: org_study_id
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