Effects of Different Ventilatory Strategy During Bronchoscopy

NCT ID: NCT05956301

Last Updated: 2023-07-21

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

150 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-07-20

Study Completion Date

2025-06-30

Brief Summary

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The execution of diagnostic-therapeutic investigations by bronchial endoscopy can expose the patient to hypoxemia. For this reason, oxygen therapy is administered at low or high flows during the course of bronchoscopic procedures.

Our study aim was to evaluate the efficacy and complications of High-flow nasal oxygen (HFNO) via Supraglottic jet oxygenation and ventilation (SJOV)during flexible bronchoscopy.

Detailed Description

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Conditions

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Bronchoscopy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

Study Groups

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Group I

Conventional Oxygen Therapy

Group Type ACTIVE_COMPARATOR

Conventional Oxygen Therapy

Intervention Type DEVICE

Conventional Oxygen Therapy will be administered through Nasal catheter

Group II

High-flow nasal oxygen

Group Type EXPERIMENTAL

High-flow nasal oxygen

Intervention Type DEVICE

High Flow Nasal Cannula will be administered

Group III

Supraglottic jet oxygenation and ventilation

Group Type EXPERIMENTAL

Supraglottic jet oxygenation and ventilation

Intervention Type DEVICE

Nasal jet tube will be administered

Interventions

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Conventional Oxygen Therapy

Conventional Oxygen Therapy will be administered through Nasal catheter

Intervention Type DEVICE

High-flow nasal oxygen

High Flow Nasal Cannula will be administered

Intervention Type DEVICE

Supraglottic jet oxygenation and ventilation

Nasal jet tube will be administered

Intervention Type DEVICE

Eligibility Criteria

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Inclusion Criteria

* need for bronchial endoscopy

Exclusion Criteria

* life-threatening cardiac aritmia or acute miocardical infarction within 6 weeks need for invasive or non invasive ventilation presence of pneumothorax or pulmonary enphisema or bullae recent (within 1 week) thoracic surgery presence of chest burns presence of tracheostomy pregnancy nasal or nasopharyngeal diseases dementia lack of consent or its withdrawal
Minimum Eligible Age

18 Years

Maximum Eligible Age

85 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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The First Affiliated Hospital of Guangzhou Medical University

OTHER

Sponsor Role lead

Responsible Party

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Liya Lu

associate chief physician

Responsibility Role PRINCIPAL_INVESTIGATOR

Central Contacts

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Liya Lu

Role: CONTACT

+86-020-83062885

Other Identifiers

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20230618

Identifier Type: -

Identifier Source: org_study_id

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