Nasal Airflow to Modulate Dyspnea in Tracheostomized Patients
NCT ID: NCT07308171
Last Updated: 2025-12-29
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
24 participants
INTERVENTIONAL
2026-02-28
2027-02-28
Brief Summary
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Detailed Description
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The hypothesis of the present study is that restoring nasal stimulation alleviates dyspnea and improves respiratory drive. The aim of this study is to compare three non-pharmacological approaches designed to restore nasal stimulation (continuous nasal airflow, nasal sprays, and facial airflow) in tracheotomized patients dependent on mechanical ventilation.
Conditions
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Keywords
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Study Design
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RANDOMIZED
SINGLE_GROUP
TREATMENT
NONE
Study Groups
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Patients
Baseline ventilator settings under pressure support
Baseline
patient ventilated through the tracheostomy with initial ventilator settings
Installation of high flow humidified air cannula
Installation of high flow humidified air cannula with FiO2 21%
Nasal air puffs
Nasal air puffs synchronized with the inspiratory time of the ventilator
FAN
Stand-alone fan at the bedside directed toward the face of the patient
Interventions
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Baseline
patient ventilated through the tracheostomy with initial ventilator settings
Installation of high flow humidified air cannula
Installation of high flow humidified air cannula with FiO2 21%
Nasal air puffs
Nasal air puffs synchronized with the inspiratory time of the ventilator
FAN
Stand-alone fan at the bedside directed toward the face of the patient
Eligibility Criteria
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Inclusion Criteria
2. Tracheostomy and mechanical ventilation
3. Dyspnea ≥3
4. Consent to participate
5. Affiliation to health insurance
Exclusion Criteria
2. Continuous use of sedatives
3. Patients under law protection
4. Inmates
5. Patients without health insurance
6. Breastfeeding and pregnancy
18 Years
ALL
No
Sponsors
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Assistance Publique - Hôpitaux de Paris
OTHER
Responsible Party
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Principal Investigators
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Martin Dres, MD PhD
Role: PRINCIPAL_INVESTIGATOR
Assistance Publique - Hôpitaux de Paris
Central Contacts
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Other Identifiers
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APHP251423
Identifier Type: -
Identifier Source: org_study_id