The Value of MRI in Assessing the Status of Retroperitoneal Resection Margin in Colon Cancer

NCT ID: NCT05859581

Last Updated: 2023-05-16

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

29 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-04-02

Study Completion Date

2023-08-31

Brief Summary

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The goal of this clinical trial is to explore the value of colon MRI in assessing the status of retroperitoneal resection margin (RPRM) for advanced colon cancer.

The main questions it aims to answer are:

* Concordance between MRI suspected RPRM positive and pathologically confirmed positive.
* Can RPRM-positive patients undergo beyond complete mesocolic excision (CME) surgery in order to achieve R0 resection?

Participants will undergo colon MRI examination and once MRI suspects RPRM positive, they will receive beyond CME surgery.

Detailed Description

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Conditions

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Colon Cancer

Study Design

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Allocation Method

NA

Intervention Model

SINGLE_GROUP

Primary Study Purpose

DIAGNOSTIC

Blinding Strategy

NONE

Study Groups

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Suspected positive RPRM on MRI

Group Type EXPERIMENTAL

Beyond complete mesocolic excision surgery

Intervention Type PROCEDURE

If the participants were diagnosed with positive retroperitoneal resection margin (RPRM), they underwent beyond complete mesocolic excision surgery to ensure the R0 resection.

Interventions

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Beyond complete mesocolic excision surgery

If the participants were diagnosed with positive retroperitoneal resection margin (RPRM), they underwent beyond complete mesocolic excision surgery to ensure the R0 resection.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* primary colon adenocarcinoma confirmed by biopsy
* preoperative CT suspecting retroperitoneal resection margin (RPRM) positive
* received colon MRI scan
* underwent beyond complete mesocolic excision surgery
* sufficient clinical and pathological results

Exclusion Criteria

* combined with other malignant tumors
* simultaneous distant metastasis
* definite invaded other organs or structures (T4b tumors)
Minimum Eligible Age

18 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Cancer Hospital & Institute

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Ying-Shi Sun, MD

Role: PRINCIPAL_INVESTIGATOR

Peking University Cancer Hospital & Institute

Locations

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Beijing Cancer Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Zhen Guan, MD

Role: CONTACT

861088196825

Facility Contacts

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Zhen Guan, MD

Role: primary

861088196825

Other Identifiers

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Colon MRI-2023-01

Identifier Type: -

Identifier Source: org_study_id

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