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Diagnostic Value of Whole-Body MRI for Rectal Cancer Preoperative Staging

NCT ID: NCT01745874

Last Updated: 2012-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

20 participants

Study Classification

OBSERVATIONAL

Study Start Date

2012-10-31

Study Completion Date

2013-10-31

Brief Summary

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The purpose of this study is to determine whether whole-body MRI (WB-MRI) accuracy is superior to FDG-PET-CT considered as the gold-standard for the staging of distant lesions of rectal cancer.

Detailed Description

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Rectal cancer is the second cause of mortality after lung cancer in industrialized countries and represent 28% of colorectal carcinomas. Despite major improvements in diagnosis and treatment made those last years,mortality and morbidity remains high, because of high prevalence of metastasis and local recurrence. A accurate initial staging is of paramount importance for an appropriate treatment (neoadjuvant chemiotherapy and radiotherapy, surgery).

Actually, there is no international consensus concerning imaging for the staging of rectal cancer and modalities used are variable from one center to another.

WB-MRI represented a attractive and promising technique for the staging of rectal cancer, free of ionizing radiation .

Conditions

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Rectal Cancer

Keywords

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Rectal cancer Whole-body MRI FDG-PET-CT preoperative staging

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Eligibility Criteria

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Inclusion Criteria

* rectal cancer T3 N+ or T3 or T4

Exclusion Criteria

* renal failure
* allergy to iodinated contrast medium
* contraindication to MRI
Minimum Eligible Age

18 Years

Maximum Eligible Age

95 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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University of Lausanne Hospitals

OTHER

Sponsor Role lead

Responsible Party

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Milena Cerny

Dr. Milena Cerny

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Milena Cerny

Role: PRINCIPAL_INVESTIGATOR

University of Lausanne Hospitals

Sabine Schmidt Kobbe, Dr.

Role: PRINCIPAL_INVESTIGATOR

University of Lausanne Hospitals

Locations

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University of Lausanne Hospitals

Lausanne, Canton of Vaud, Switzerland

Site Status RECRUITING

Countries

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Switzerland

Facility Contacts

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Milena Cerny, Resident

Role: primary

Sabine Schmidt Kobbe, MER

Role: backup

Other Identifiers

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247/12

Identifier Type: -

Identifier Source: org_study_id