BMAC Loaded Collagen Jumping the Gap Around Immediate Implants

NCT ID: NCT05817526

Last Updated: 2024-03-28

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-01-25

Study Completion Date

2024-12-31

Brief Summary

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The present study aims to evaluate the effect of utilization of BMAC/ collagen on marginal bone changes around immediate implants in the esthetic zone of maxilla.

Methodology: Twenty dental implants will be installed in the esthetic zone and patients will be randomly divided into two groups:

study group: The jumping gap surrounding the immediate implants will be grafted with BMAC/collagen, whereas in the control group, autograft from the chin will be used to fill the defect. Cone beam CT (CBCT) will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around implants.

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Detailed Description

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The aim of present study is to evaluate the effect of utilization of bone marrow aspirate concentrate (BMAC) loaded on collagen on the marginal bone changes around immediate implants in the esthetic zone of maxilla.

Methodology: Twenty dental implants will be installed in patients suffering from non- restorable teeth in esthetic zone.

Patients will be randomly divided into two equal groups:

study group: The jumping gap surrounding the immediate implants will be grafted with bone marrow aspirate concentrate loaded on collagen, whereas in the control group, autogenous bone graft from the chin will be used to fill the peri-implant defect. CBCT will be requested Preoperative, immediate and 4 months Postoperative for assessment of marginal bone changes around dental implants.

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Conditions

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Implant Site Reaction Dental Implantation

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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BMAC/ collagen

Bone marrow aspirate concentrate loaded on collagen utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone

Group Type ACTIVE_COMPARATOR

BMAC/ collagen

Intervention Type DRUG

Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect

Autograft

Autograft harvested from chin utilization for filling peri-implant gap around immediate dental implants in the Maxillary esthetic zone

Group Type ACTIVE_COMPARATOR

Autograft harvesting from chin

Intervention Type PROCEDURE

Autograft

Interventions

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BMAC/ collagen

Bone marrow aspirate concentrate loaded on collagen in the peri-implant defect

Intervention Type DRUG

Autograft harvesting from chin

Autograft

Intervention Type PROCEDURE

Other Intervention Names

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Bone marrow aspirate concentrate group Autograft group

Eligibility Criteria

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Inclusion Criteria

* Patients with non- restorable teeth in esthetic zone
* Patients above 18 us
* Highly motivated patients.

Exclusion Criteria

* patients with systemic diseases • immunocompromised patients . Patients with bleeding disorders
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Walaa Kadry

Lecturer of oral and Maxillofacial Surgery

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Eman Said

Role: STUDY_DIRECTOR

Lecturer at Faculty of Dentistry, Cairo University

Locations

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Walaa Kadry

Cairo, , Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Walaa Kadry

Role: CONTACT

+201061527359

Ahmed Amin

Role: CONTACT

Facility Contacts

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Wael Abdel samee

Role: primary

Other Identifiers

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BMAC around immediate implants

Identifier Type: -

Identifier Source: org_study_id

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