Immediate Implant Placement in Aggressive Periodontitis
NCT ID: NCT03218228
Last Updated: 2017-07-18
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
20 participants
INTERVENTIONAL
2017-06-10
2018-12-08
Brief Summary
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Detailed Description
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After wards, microbial theory was modified to enroll the genetic background that can be the cause behind the developed body resistance. Although the importance of the genetic treatment to improve the body response, it was totally dismissed during the routine periodontal work attributable to high cost effectiveness of the needed genetic analysis especially in developing countries.
Further researches tried to explain the cause behind the impaired body response. Impaired functions of the immune cells and the massive amounts of catabolic cytokines such as IL-1, IL-6, Il-17, TNF- α and prostaglan¬din E2 (PGE2) are usually released during the active periods of the disease. On the other hand, matrix-metalloproteinases are destructive enzymes that released in an uncontrollable manner. Host modulators were suggested to control the released of the destructive agents.
Immediate implant placement provides an efficient modality that shortens the dental management period. The aim behind immediate implant placement is the proper implant positioning to counteract the advanced bone resorption following extraction.
Periodontitis is considered an important risk factor for peri-implantitis. The pre-existing periodontitis must be treated prior to implant placement in order to avoid the bacterial accumulation in the periodontal lesions regardless the type of periodontitis. Local and systemic supportive therapy is strongly recommended in order to reduce the microbial colonies and post-operative bone loss.
Higher rate of implant failure (peri-implantitis) has been reported in immediately placed implants when compared with the delayed conventional technique. The failure rate markedly increased with the immediate placement of implants in patients with history of periodontitis especially the aggressive form.
Conditions
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Study Design
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NON_RANDOMIZED
PARALLEL
HEALTH_SERVICES_RESEARCH
NONE
Study Groups
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implants in healthy individuals
immediate placement of dental implants in individuals with healthy periodontium. the device is dental implants, radiographs, william's periodontal probe
implants in periodontitis
it targets immediate implant placement in patients suffering from aggressive periodontitis
implants in periodontitis patients
immediate implantation in patients suffering from aggressive periodontitis. the device is the dental implants, radiographs, william's periodontal probe
implants in periodontitis
it targets immediate implant placement in patients suffering from aggressive periodontitis
Interventions
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implants in periodontitis
it targets immediate implant placement in patients suffering from aggressive periodontitis
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients should be free from any systemic disease.
* patients with good oral hygiene
* completely or partially edenthulus patients
Exclusion Criteria
* Pregnant females.
* Patients with systemic diseases that may interfere with periodontal condition
* Uncooperative patients
18 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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nermin mohammed ahmed yussif
principal investigator-faculty of oral and dental medicine
Principal Investigators
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mona darhous, Prof
Role: STUDY_DIRECTOR
faculty of oral and dental medicine cairo university
Locations
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Octobar University of Modern Sciences and Arts
Giza, , Egypt
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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immediate implant
Identifier Type: -
Identifier Source: org_study_id
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