Comparison of Peri Implant Soft Tissue Esthetics With Immediate Temporization With and Without Subepithelial Connective Tissue Graft

NCT ID: NCT03770975

Last Updated: 2018-12-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

PHASE3

Total Enrollment

22 participants

Study Classification

INTERVENTIONAL

Study Start Date

2018-12-01

Study Completion Date

2020-05-01

Brief Summary

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The aim of this study is to clinically evaluate peri-implant soft tissue esthetics around single delayed implants in the esthetic zone.

Detailed Description

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To compare the efficacy of soft tissue augmentation on the peri-implant soft tissue esthetics along with immediate temporization to immediate temporization only.

Population (P): patients with a single missing tooth in the esthetic zone Intervention (I): Delayed implant placement with immediate temporization and subepithelial connective tissue graft Comparator (C): Delayed implant placement with immediate temporization Primary outcome: Pink esthetic score (PES) Time frame: 6 months Study design: Randomized controlled clinical trial

Conditions

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Immediate Temporization and Soft Tissue Augmentation Around Delayed Implants

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Delayed implant placement with immediate provisionalization

Single delayed implant placement in the esthetic zone with placing an immediate temporary crown placed within 48 hours after the surgery

Group Type ACTIVE_COMPARATOR

delayed implant with immediate provisionaliztion and soft tissue graft

Intervention Type PROCEDURE

delayed implant placement in the esthetic zone with immediate provisinalization and placement of a connective tissue graft buccal

Implant with immediate temporization and soft tissue graft

Single delayed implant placement in the esthetic zone with placing a subepithelial connective tissue graft buccal to the implant and immediate temporary crown within 48 hours after the surgery

Group Type EXPERIMENTAL

delayed implant placement with immediate provisionalization

Intervention Type PROCEDURE

delayed implant placement with immediate provisionalization

Interventions

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delayed implant with immediate provisionaliztion and soft tissue graft

delayed implant placement in the esthetic zone with immediate provisinalization and placement of a connective tissue graft buccal

Intervention Type PROCEDURE

delayed implant placement with immediate provisionalization

delayed implant placement with immediate provisionalization

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

1. Age \> 18 years old
2. Good medical and psychological health
3. Absence of untreated caries lesions and untreated/uncontrolled periodontal disease. If patients required periodontal treatment (non-surgical and/or surgical), this was arranged outside the study protocol and completed at least 30 days prior to the enrolment
4. Need of a single-tooth replacement in the aesthetic (incisor, canine or premolar) region
5. Willingness to sign the informed consent form

Exclusion Criteria

1. Any known disease (not including controlled diabetes mellitus), infections or recent surgical procedures within 30 days of study initiation;
2. Chronic treatment (i.e., 2 weeks or more) with any medication known to affect oral status (e.g., phenytoin, dihydropyridine, calcium antagonists and cyclosporine) within 1 month before baseline visit;
3. Anticoagulant therapy with warfarin, clopidogrel, ticlopidine or once daily aspirin (more than 81 mg);
4. HIV or Hepatitis;
5. Physical handicaps that would interfere with the ability to perform adequate oral hygiene;
6. Alcoholism or chronic drug abuse;
7. Heavy smokers (\>10/cigarettes per day);
8. Lack of adequate primary stability at implant insertion that enables immediate provisionalization (insertion torque ca 30 Ncm).
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Cairo University

OTHER

Sponsor Role lead

Responsible Party

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Dina Osama Abdelwahab Megahed

Resident

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Azza Ezz AlArab, PHD

Role: STUDY_CHAIR

Professor in the department of Oral Medicine and Periodontology

Locations

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Faculty of Dentistry, Cairo University

Cairo, , Egypt

Site Status

Countries

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Egypt

Central Contacts

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Dina Osama, Bachelor

Role: CONTACT

Phone: 01003808409

Email: [email protected]

Hany ElNahass, PHD

Role: CONTACT

Phone: 01000252603

Email: [email protected]

Facility Contacts

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Hany ElNahass, PHD

Role: primary

References

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Abdelwahab D, Ezz AlArab A, El Nahass H. Soft tissue esthetics around immediately provisionalized delayed implants with and without connective tissue graft: A randomized clinical trial pilot study. Clin Implant Dent Relat Res. 2023 Feb;25(1):11-22. doi: 10.1111/cid.13168. Epub 2022 Dec 29.

Reference Type DERIVED
PMID: 36579756 (View on PubMed)

Other Identifiers

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Dinaosamaperio

Identifier Type: -

Identifier Source: org_study_id