Effect of Dairy on Cognitive Performance in Children

NCT ID: NCT05767983

Last Updated: 2024-07-18

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

54 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-10-18

Study Completion Date

2023-10-31

Brief Summary

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The purpose of this study is to determine the effects of dairy consumption on short-term cognitive performance, subjective mood and emotions, and glycemic response in healthy children aged 9 - 14 years. The investigators hypothesize that the consumption of dairy products as a mid-morning snack will improve mood and cognitive performance in children. Furthermore, the investigators hypothesize that all dairy products consumed as a mid-morning snack will imbue more benefits on mood and cognitive performance over 2-hours compared to fruit juice or snack skipping.

Detailed Description

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A randomized within-subject repeated measures experiment will be used to study the effects of dairy product consumption on cognitive performance, subjective mood and emotions, and blood glucose in healthy 9 - 14 year old children. Participants will consume, in a random order on separate mornings, one of the five treatments: (a) milk, (b) yogurt, (c) cheese, (d) fruit juice, or (e) snack skipping. Subjective mood/emotions and cognitive domains (learning and memory, spatial working memory, attention, processing speed, and executive function) will be assessed at baseline (0-min), and 15-, 30-, 60-, and 120-min following treatment consumption. Blood glucose measurements will be collected using the Freestyle Libre 2 continuous glucose monitoring system.

Conditions

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Children Healthy

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

PREVENTION

Blinding Strategy

NONE

Study Groups

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Fat-free milk

Treatment

Group Type EXPERIMENTAL

Fat-free milk

Intervention Type OTHER

Fat-free milk (500 mL, skim, 0%, Lactantia PurFiltre) will provide 180 kcal, 0 g fat, 26 g carbohydrate, and 18 g protein. Treatments matched for calories (180 kcal).

Fat-free yogurt

Treatment

Group Type EXPERIMENTAL

Fat-free yogurt

Intervention Type OTHER

Fat-free yogurt (242 g, vanilla, 0% Greek, Oikos) will provide 180 kcal, 0 g fat, 23.5 g carbohydrate, and 19.4 g protein. Treatments matched for calories (180 kcal).

Low-fat cheese

Treatment

Group Type EXPERIMENTAL

Low-fat cheese

Intervention Type OTHER

Low-fat cheese (60 g, mild marble cheddar, 40% less fat, Selection) will provide 180 kcal, 10 g fat, 2 g carbohydrate, and 16 g protein. Treatments matched for calories (180 kcal).

Fruit juice

Treatment

Group Type EXPERIMENTAL

Fruit juice

Intervention Type OTHER

Fruit juice (450 mL, Fruité® Fruit Punch) will provide 180 kcal, 0 g fat, 46.8 g carbohydrate, and 0 g protein. Treatments matched for calories (180 kcal).

Snack skipping

Treatment

Group Type EXPERIMENTAL

Snack skipping

Intervention Type OTHER

Water control treatment (no caloric contribution). Matched for volume (500 mL) to fat-free milk treatment.

Interventions

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Fat-free milk

Fat-free milk (500 mL, skim, 0%, Lactantia PurFiltre) will provide 180 kcal, 0 g fat, 26 g carbohydrate, and 18 g protein. Treatments matched for calories (180 kcal).

Intervention Type OTHER

Fat-free yogurt

Fat-free yogurt (242 g, vanilla, 0% Greek, Oikos) will provide 180 kcal, 0 g fat, 23.5 g carbohydrate, and 19.4 g protein. Treatments matched for calories (180 kcal).

Intervention Type OTHER

Low-fat cheese

Low-fat cheese (60 g, mild marble cheddar, 40% less fat, Selection) will provide 180 kcal, 10 g fat, 2 g carbohydrate, and 16 g protein. Treatments matched for calories (180 kcal).

Intervention Type OTHER

Fruit juice

Fruit juice (450 mL, Fruité® Fruit Punch) will provide 180 kcal, 0 g fat, 46.8 g carbohydrate, and 0 g protein. Treatments matched for calories (180 kcal).

Intervention Type OTHER

Snack skipping

Water control treatment (no caloric contribution). Matched for volume (500 mL) to fat-free milk treatment.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* 9 to 14 years of age;
* Normal weight defined as between the 15th and 80th percentile for age and biological sex at birth according to the World Health Organization growth (WHO) charts.

Exclusion Criteria

* Children with overweight/ obesity;
* Children with food sensitivities or allergies to dairy, gluten or any foods used in the study;
* Children with any diagnosed learning, emotional, or behavioural disabilities;
* Children taking any medications that may influence cognitive performance.
Minimum Eligible Age

9 Years

Maximum Eligible Age

14 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Dairy Management Inc.

INDUSTRY

Sponsor Role collaborator

National Dairy Council

OTHER

Sponsor Role collaborator

Toronto Metropolitan University

OTHER

Sponsor Role lead

Responsible Party

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Nick Bellissimo, PhD

Associate Professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Nick Bellissimo, PhD

Role: PRINCIPAL_INVESTIGATOR

Toronto Metropolitan University

Locations

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Centre for Urban Innovation (CUI-109), Toronto Metropolitan University (Formerly Ryerson University)

Toronto, Ontario, Canada

Site Status

Countries

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Canada

Other Identifiers

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Temp ID

Identifier Type: -

Identifier Source: org_study_id

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