Comparison Between Negative Pressure Wound Therapy and Conventional Wound Dressings Before and After Split-Thickness Skin Grafting in Diabetic Foot Wounds

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-02-01

Study Completion Date

2024-04-30

Brief Summary

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The aim of this thesis is to compare the efficacy of Vacuum assisted closure device versus conventional dressing before and after split thickness skin grafting in diabetic foot wounds.

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Detailed Description

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Negative pressure wound therapy is a new noninvasive technique for treating open wounds. It works by removing fluid from the wound bed, reducing edema, and encouraging the growth and perfusion of new granulation tissue.

Vacuum-Assisted Closure device (VAC) helps to remove fluid from open wounds through a sealed dressing and tubing which is connected to a collection container. Vacuum-assisted closure (VAC) can provide stable and persistent negative pressure, and there are several modes to choose from.

VAC has played an important role in helping to close wounds, controlling infection, promoting angiogenesis, increasing blood flow, and promoting granulation tissue growth in wounds. It is now widely applied in all kinds of acute, chronic, and special wounds with good therapeutic results. However, there is a need to pay attention to contraindications and complications of VAC when it is used, avoiding secondary damage due to improper treatment.

Conditions

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Negative-Pressure Wound Therapy Diabetic Foot

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Patients will randomly be divided into two groups - study group and control group. Study group (A): Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting.

Control group (B): Will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.

Primary Study Purpose

SUPPORTIVE_CARE

Blinding Strategy

NONE

Study Groups

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Study group (A)

Study group (A): Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting.

Group Type EXPERIMENTAL

Negative Pressure Wound Therapy (NPWT)

Intervention Type DEVICE

Patients Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting.

Control group (B)

Control group (B): Will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.

Group Type EXPERIMENTAL

Ordinary dressings with antibiotic ointment and gauze

Intervention Type OTHER

Patients will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.

Interventions

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Negative Pressure Wound Therapy (NPWT)

Patients Will Receive negative pressure wound therapy dressings before skin grafting to prepare the wound bed and after skin grafting.

Intervention Type DEVICE

Ordinary dressings with antibiotic ointment and gauze

Patients will Receive once daily dressing with antibiotic ointment and gauze before and after skin grafting.

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* Age group 20-75 years.
* Patients with diabetic foot wounds who are scheduled for skin grafting.

Exclusion Criteria

* Age \<20 years or \> 75 years.
* An obvious septicemia.
* Foot osteomyelitis.
* Ulcer resulting from venous insufficiency.
* Features of malignant ulcer.
* Patients being treated with corticosteroids, immunosuppressive drugs.
* Any other serious pre-existing cardiovascular, pulmonary or immunological disease.

Minimum Eligible Age

20 Years

Maximum Eligible Age

75 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No