The Taste and Acceptability of a High Protein Ice Cream Compared With Hospital Milkshake Nutritional Supplement

NCT ID: NCT05711277

Last Updated: 2023-02-10

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

50 participants

Study Classification

INTERVENTIONAL

Study Start Date

2022-06-20

Study Completion Date

2022-09-01

Brief Summary

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This study aims to compare the acceptability of a new high protein, fortified, ice cream called Nottingham-Ice cream (N-ICE CREAM) with a standard milkshake-style oral nutritional supplement (ONS); Fortisip Compact Protein in older patients admitted to hospital with fractures who require ONS as part of routine care.

Detailed Description

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Older adults admitted to hospital with fractures are often vulnerable to malnutrition. The European Society for Clinical Nutrition and Metabolism guidelines on clinical nutrition and hydration in geriatrics recommend 'older patients with hip fracture shall be offered ONS post-operatively to improve dietary intake and reduce risk of complications'.

As part of routine care at Nottingham University Hospitals (NUH) NHS Trust patients with femoral fragility fractures and vertebrae fractures are prescribed a milkshake style ONS called Fortisip Compact protein twice daily. Poor compliance (amount consumed relative to amount prescribed) to ONS in older adults has been reported in scientific literature with our own research findings reporting 28% compliance to standard milkshake ONS in older trauma and orthopaedic patients. There is a need for an ONS which patients accept and enjoy, of which ice cream has the strong possibility of accomplishing. There few studies to date exploring the potential of ice cream as a nutritional intervention. Ice cream has proven successful improving quality of life and shown favourable among oncological patients with 88% reporting they would rather eat ice cream that conventional nutritional supplements. Furthermore, research in ortho-geriatric patients at NUH showed an increase in energy intake by 41% for those consuming a high energy and protein ice cream. These encouraging results highlight the need for further scientific research to explore ice cream as an ONS.

This study aims to further explore compliance to N-ICE CREAM compared to standard ONS. This is a randomised crossover study. Participants admitted to hospital with hip or spine fractures and requiring ONS for the duration of their hospital stay only as part of routine care will receive N-ICE CREAM for two days and standard ONS for two days in a random order. Participants will complete acceptability and attitudes questionnaire for each product in additional to a questionnaire about the feasibility of having N-ICE CREAM at home. Compliance to each product will also be monitored and preference noted.

Overview of the study:

1. Patients will be assessed for inclusion and exclusion criteria by the research team, and then provided with information about the study. Patients eligible to take part will be asked for written informed consent or nominated consultee consent sought from patients without capacity. Participant demographics and medical history will be collected from online hospital systems and medical notes.
2. Participants will be randomly allocated to receive either:

A. N-ICE CREAM twice a day for two days; N-ICE CREAM tub size approximately 80g (1.96kcal/g, 0.19g protein/g) followed by a standard milkshake based ONS; Fortisip Compact Protein twice a day for two days; serving size 125ml (2.4kcal/g, 0.14g protein/g).

B. A standard milkshake based ONS; Fortisip Compact Protein twice a day for two days followed by N-ICE CREAM twice a day for two days.

The hypothesis is that N-ICE CREAM will be 'as accepted', if not more accepted, than the milkshake ONS. The results from this study will guide future nutritional interventions for older adults admitted to hospital with fractures.

Conditions

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Femoral Fragility Fractures Malnutrition

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

CROSSOVER

Primary Study Purpose

BASIC_SCIENCE

Blinding Strategy

NONE

Study Groups

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N-ICE CREAM

Group Type EXPERIMENTAL

High protein, fortified, ice cream

Intervention Type DIETARY_SUPPLEMENT

Two 80g servings of N-ICE CREAM administered a day for two days

Milkshake ONS

Group Type ACTIVE_COMPARATOR

Standard milkshake ONS (Fortisip Compact Protein)

Intervention Type DIETARY_SUPPLEMENT

Two 125ml bottles of standard ONS administered a day for two days

Interventions

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Standard milkshake ONS (Fortisip Compact Protein)

Two 125ml bottles of standard ONS administered a day for two days

Intervention Type DIETARY_SUPPLEMENT

High protein, fortified, ice cream

Two 80g servings of N-ICE CREAM administered a day for two days

Intervention Type DIETARY_SUPPLEMENT

Other Intervention Names

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ONS Sip feeds Oral nutritional supplements N-ICE CREAM Nottingham-Ice cream

Eligibility Criteria

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Inclusion Criteria

* Patients aged 65 years and over admitted to QMC hospital.
* Patients capable of giving informed consent, or if appropriate, participants having a personal consultee able to complete a declaration in favour of the patient participating in the trial.
* Patients with a diagnosed hip or spine fracture requiring ONS as part of the routine nutritional pathway.
* Patients who have had malnutrition risk assessed by the Malnutrition Universal Screening Tool (MUST) and have a MUST score of 0 or 1.
* Patients with an anticipated length of stay ≥ 4 days.

Exclusion Criteria

* Patients \< 65 years old.
* Patients scheduled for total parenteral nutrition or tube feeding.
* Patients with a MUST ≥ 2.
* Clinically unstable patients (e.g. in terminal condition end of life situation).
* Patients with medical or dietary contraindication to any feed ingredients (e.g. with known allergies or intolerance to any ingredients in the N-ICE CREAM or FSCP).
* Patients with significant renal impairment (chronic kidney disease stages 4 and 5).
* Any contraindication against nutritional therapy (includes paralytic ileus\< inborn errors of metabolism of nutrients contained in N-ICE CREAM or FSCP).
Minimum Eligible Age

65 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Nottingham University Hospitals NHS Trust

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Locations

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Queens Medical Centre

Nottingham, Nottinghamshire, United Kingdom

Site Status

Countries

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United Kingdom

Other Identifiers

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22HC002

Identifier Type: -

Identifier Source: org_study_id

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