China Nutrition Fundamental Data 2020

NCT ID: NCT05694104

Last Updated: 2023-01-23

Basic Information

• Recruitment Status: COMPLETED
• Total Enrollment: 54677 participants
• Study Classification: OBSERVATIONAL
• Study Start Date: 2020-08-24
• Study Completion Date: 2022-01-07

Brief Summary

Malnutrition caused by reduced food intake or assimilation and varying degrees of acute or chronic inflammation is a serious and underappreciated risk factor for adverse clinical outcomes. Despite the substantial health and economic burden, malnutrition remains to affect a considerable proportion of hospitalized patients worldwide. Nationally representative studies from the USA, Australia, and European countries have reported prevalence figures in the range of 8.9% to 80.4%. However, national data in some resource-poor countries, such as China, the largest developing country in the world, are scarce.

We did the China Nutrition Fundamental Data 2020 in a large, nationally representative sample of Chinese adult inpatients to 1) Explore the relationship between nutrition and health; 2) Understand the capacity of nutrition services in Chinese medical institutions.

This project adopted a multistage, stratified, cluster-sampling procedure based on administrative divisions in China. For each participant, a structured interview was done by trained nutritionists or clinicians. The following data were acquired: weight change within and beyond six months, food intake change within two weeks, nutrition therapy during this hospitalization, and laboratory tests. We also collected information on participants' sociodemographic characteristics and medical history. We took physical measurements, including height, weight, waist circumference, hip circumference, mid-arm circumference, calf circumference, handgrip strength, and blood pressure following standard protocols. Body composition was measured using bioimpedance analysis (BIA). In total, 54677 inpatients from 291 project hospitals completed information collection.

In addition, we collected information on the number of beds, the nutrition support team, the nutrition treatment plan and the construction of a full-time nutrition physician or nutrition nurse, the routine monitoring methods, interventions, and distribution of brochures for patients with malnutrition or nutritional risk in each project hospital and 37 other hospitals based on the principle of voluntary participation. A total of 328 hospitals completed information collection.

This project will establish standards for nutrition risk assessment, diagnosis, and treatment of inpatients in China, promote the construction of clinical nutrition departments, and improve the nutritional status of inpatients.

Conditions

Nutritional Status of Chinese Inpatients；Nutritional Service Capacity of Medical Institutions in China

Study Design

• Observational Model Type: ECOLOGIC_OR_COMMUNITY
• Study Time Perspective: CROSS_SECTIONAL

Interventions

Malnutrition

For the diagnosis of malnutrition, we adopted the Global Leadership Initiative on Malnutrition (GLIM) scheme based on three phenotypic criteria (non-volitional weight loss, low body mass index, and reduced muscle mass) and two etiologic criteria (reduced food intake or assimilation, and inflammation or disease burden). To diagnose malnutrition at least one phenotypic criterion and one etiologic criterion should be present in patients with nutritional risk.

Intervention Type: OTHER

Eligibility Criteria

Inclusion Criteria

• Aged 18 years or older
• Admitted to hospital within 24-48 hours (not emergency) due to tumor or digestive system, respiratory system, cardiovascular system, endocrine system, nervous system, and urinary system disease.

Exclusion Criteria

• With mental illness or memory disorder who were unable to answer questions correctly
• Critically ill patients
• Lack behavioral ability

• Minimum Eligible Age: 18 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

National Institute of Hospital Administration, National Health Commission

UNKNOWN

Sponsor Role: collaborator

Peking Union Medical College Hospital

OTHER

Sponsor Role: lead

Responsible Party

Wei Chen

Professor

Responsibility Role: PRINCIPAL_INVESTIGATOR

Locations

Dongcheng district，Peking union medical college hospital

Beijing, Beijing Municipality, China

Countries

China

References

Deng LM, Liu SP, Long JF, Mo H, Liu M, Liu JY, Zhang YL, Xu DF, Yu HZ, Chen L, Cai H, Yang SB, Xiang M, Liu M, Sun Y, Xie ZJ, Zeng MM, Xie GX. Prevalence of malnutrition and appropriateness of nutritional support in hospitalized patients: a GLIM-based study. Front Nutr. 2025 Oct 10;12:1667821. doi: 10.3389/fnut.2025.1667821. eCollection 2025.

Reference Type: DERIVED

PMID: 41141257 (View on PubMed)

Other Identifiers

ZS-2614

Identifier Type: -

Identifier Source: org_study_id