Appetite and Related Factors in Patients With ALS

NCT ID: NCT04953624

Last Updated: 2021-07-08

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

200 participants

Study Classification

OBSERVATIONAL

Study Start Date

2020-08-01

Study Completion Date

2022-03-31

Brief Summary

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Chinese cnaq scale was used to evaluate the appetite changes of Chinese ALS patients; Objective to investigate the related factors of appetite changes in ALS patients; Objective to investigate the effect of anorexia on the progression and survival of ALS patients.

Detailed Description

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1. With the consent of the original author, the scale was translated and back translated, and the Chinese version of the scale was determined after communication and confirmation with the original author.
2. Cnaq was used to measure the appetite of the patients, and hads was used to measure the anxiety and depression of the patients;
3. Analyze the proportion of loss of appetite in ALS group, compare the differences of clinical characteristics such as ALSFRS-R score, weight, BMI value, cognitive status such as ECAs score between patients with loss of appetite and patients without loss of appetite in ALS group, and conduct correlation analysis.
4. The patients were followed up every three months until they were unable to eat or end-point events (invasive ventilator or death), and the correlation between cnaq and disease progression and survival was analyzed.

Conditions

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Amyotrophic Lateral Sclerosis

Study Design

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Observational Model Type

ECOLOGIC_OR_COMMUNITY

Study Time Perspective

PROSPECTIVE

Study Groups

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CNAQ≤28

ALS patients with CNAQ ≤ 28

Appetite rating scale CNAQ

Intervention Type DIAGNOSTIC_TEST

Chinese version of Appetite rating scale CNAQ

CNAQ>28

ALS patients with CNAQ \> 28

Appetite rating scale CNAQ

Intervention Type DIAGNOSTIC_TEST

Chinese version of Appetite rating scale CNAQ

Interventions

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Appetite rating scale CNAQ

Chinese version of Appetite rating scale CNAQ

Intervention Type DIAGNOSTIC_TEST

Eligibility Criteria

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Inclusion Criteria

* ALS patients diagnosed as probable, or definite according to the revised El Escorial criteria

Exclusion Criteria

* there are other chronic consumption diseases such as severe digestive system diseases, thyroid diseases, diabetes and so on.
Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Peking University Third Hospital

OTHER

Sponsor Role lead

Responsible Party

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Responsibility Role SPONSOR

Principal Investigators

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Dongsheng Fan

Role: PRINCIPAL_INVESTIGATOR

Peking University Third Hospital

Locations

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Peking University Third Hospital

Beijing, Beijing Municipality, China

Site Status RECRUITING

Countries

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China

Central Contacts

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Dongsheng Fan

Role: CONTACT

+86 13701023871

Facility Contacts

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Dongsheng Fan

Role: primary

Other Identifiers

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M2020399

Identifier Type: -

Identifier Source: org_study_id

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