MedDataX Logo

Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries

NCT ID: NCT05688293

Last Updated: 2025-02-11

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-02-05

Study Completion Date

2026-03-01

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Thin gingival phenotype is one of the major causative factors of gingival recession type 1 which can result in hypersensitivity, discomfort, and compromised esthetics. This study assess the efficacy of increasing the gingival thickness from thin gingival phenotype to thick gingival phenotype in the treatment of patients suffering from gingival recession (RT1) and maintenance of results using either connective tissue graft or de-epithelized free gingival graft after non-surgical periodontal debridement compared to non-surgical periodontal debridement alone.

Related Clinical Trials

Explore similar clinical trials based on study characteristics and research focus.

Time Effect on the Predictability of Different Grafting for Gingival Recession RT 1

NCT05976451

Gingival Recession Types One(RT1)
COMPLETED NA

Clinical Evaluation of the Modified Laterally Stretched Technique (RT2) Gingival Recession vs Tunneling With CT Grafting

NCT06044870

Gingival Recession
ACTIVE_NOT_RECRUITING NA

Evaluation of SECTG Vs. Laser-DGG in Management of Gingival Recessions.

NCT04133298

Gingival Recession
COMPLETED NA

Treatment of Gingival Recession Using Gingival Composite Restoration Versus Coronally Advanced Flap

NCT04584931

Gingival Recession
UNKNOWN NA

Soft Tissue Augmentation Using CAF With Either SCTG and Vitamin C Versus SCTG Alone in Management of RT1 Gingival Recession

NCT04632693

Gingival Thickness
UNKNOWN NA

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

This parallel arm randomized controlled clinical trial study will include systematically free patients with thin gingival phenotype. They will be randomly allocated to three equal groups. Group A (test group, n=10) will receive non-surgical periodontal treatment and connective tissue graft using tunneling technique, Group B (test group, n=10) will receive non-surgical periodontal treatment and partially de-epithelized free gingival graft, while group C (control group, n=10) will receive non-surgical periodontal treatment only. After 3, 6 and 12 months gingival biotype will be clinically assessed (1ry outcome). This parameter will be recorded at baseline, 3, 6 and 12 months. The 2ry outcomes will include recording of recession depth, plaque index, bleeding on probing, keratinized tissue width . Postoperative pain and swelling will be recorded daily by the patient for the 1st two weeks post-surgically. Postoperative instructions and medication will be given to the patient. All readings will be carried out by a calibrated outcome assessor who will be masked. Follow-up will be performed to assess the outcomes and to ensure performing proper oral hygiene. Data collected will be tabulated and statistically analyzed.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Gingival Recession

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Three parallel groups
Primary Study Purpose

TREATMENT

Blinding Strategy

DOUBLE

Participants Outcome Assessors
the patient won't know the type of the procedures done to him The outcome assessor won't know which group he the is assessing it's results

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Connective tissue graft

Patients will receive non-surgical periodontal treatment and connective tissue graft using tunneling technique

Group Type ACTIVE_COMPARATOR

Connective tissue graft

Intervention Type PROCEDURE

non-surgical periodontal treatment and connective tissue graft

Free gingival Graft

Patients will receive non-surgical periodontal treatment and partially de-epithelized free gingival graft

Group Type ACTIVE_COMPARATOR

Free gingival graft

Intervention Type PROCEDURE

will receive non-surgical periodontal treatment and partially de-epithelized free gingival graft

Non surgical procedure

Patients will receive non-surgical periodontal treatment only

Group Type ACTIVE_COMPARATOR

Non surgical

Intervention Type PROCEDURE

non-surgical periodontal treatment only

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Connective tissue graft

non-surgical periodontal treatment and connective tissue graft

Intervention Type PROCEDURE

Free gingival graft

will receive non-surgical periodontal treatment and partially de-epithelized free gingival graft

Intervention Type PROCEDURE

Non surgical

non-surgical periodontal treatment only

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Medically free patients (American Society of Anesthesiologists I; ASA I)
* Patients diagnosed with recession (RT1)
* Fair oral hygiene
* Patient accepting to provides an informed consent and the follow-up

Exclusion Criteria

* Carious teeth and teeth with periapical infection.
* Patients diagnosed with periodontitis
* Smokers
* Pregnant and lactating females
Minimum Eligible Age

18 Years

Maximum Eligible Age

55 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Misr International University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Responsibility Role SPONSOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Zainab Hafez, Lecturer

Role: PRINCIPAL_INVESTIGATOR

Lecturer, faculty of oral and dental medicine misr international university

Shahinaz Al ashiry, Asso. Prof

Role: STUDY_DIRECTOR

Associate professor, faculty of oral and dental medicine misr international university

Yahia Amer, Lecturer

Role: PRINCIPAL_INVESTIGATOR

Lecturer, faculty of oral and dental medicine misr international universit

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Faculty of oral and dental medicine, Misr international university

Cairo, , Egypt

Site Status RECRUITING

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Central Contacts

Reach out to these primary contacts for questions about participation or study logistics.

Zainab Hafez, Lecturer

Role: CONTACT

[email protected]
+01221334637

Shahinaz Al ashiry, Asso. Prof

Role: CONTACT

[email protected]

Facility Contacts

Find local site contact details for specific facilities participating in the trial.

Zainab Hafez, Lecturer

Role: primary

[email protected]

Yahia amer, Lecturer

Role: backup

[email protected]

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

PER 5213005

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Treatment of Gingival Recession With Tunnel Technique Using Connective Tissue Graft and Injectable Platelet Rich Fibrin
NCT06646432 RECRUITING NA
Impact of Microneedling on Coverage of RT1 Gingival Recession in Thin Phenotype.
NCT06432439 NOT_YET_RECRUITING NA
Effect Of Microneedling With Coronally Advanced Flap For Management of RT1 Gingival Recession In Thin Gingival Phenotype
NCT06988839 NOT_YET_RECRUITING NA
Titanium-prepared Platelet Rich Fibrin Versus Connective Tissue Graft for Management of Type-2 Gingival Recession
NCT06621433 COMPLETED NA
Comparison of Root Coverage of Gingival Recessions
NCT02980055 UNKNOWN PHASE2
Comparing Deepithelialized Free Gingival Graft Versus Subpithelial Connective Tissue Graft With Tunneling Technique in Treating RT2 Gingival Recession
NCT04104087 UNKNOWN PHASE4
Clinical Evaluation of (TCAF) Versus (CAF) Combined With Connective Tissue Graft in the Treatment of Multiple RT2 Gingival Recession Sites
NCT07064603 NOT_YET_RECRUITING NA
Guided Versus Non-Guided Harvesting Technique of Soft Tissue Graft in Cairo Recession Type I Sites
NCT06603467 ACTIVE_NOT_RECRUITING NA
Evaluation of Subepithelial Connective Tissue Graft Versus Acellular Dermal Matrix With Tunnel Technique in Treatment of Multiple Gingival Recessions
NCT02916186 UNKNOWN NA
Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
NCT05823415 UNKNOWN NA
Gingival Recession Treatment Using Two Different Surgical Techniques
NCT04966208 COMPLETED NA
Extended Platelet- Rich Fibrin Membrane Combined With Vestibular Incision Subperiosteal Tunnel Access Technique to Treat Localized Gingival Recession
NCT07079293 COMPLETED NA
Comparison of Free Gingival Graft and Linear Incision for Connective Tissue
NCT06365983 RECRUITING NA
Amnion Membrane Versus DFGG Using the Tunneling Technique in Management of Gingival Recession Defects.
NCT06146855 RECRUITING NA
Bi-layer Collagen Membrane Versus Subepithelial Connective Tissue Graft in the Treatment of Localized Gingival Recession
NCT07162207 ACTIVE_NOT_RECRUITING NA
Inverted T-shape Free Gingival Graft for Treatment of RT2 / RT3 Gingival Recession Defects
NCT06615687 NOT_YET_RECRUITING NA
Coronally Advanced Flap With Alloderm Versus Coronally Advanced Flap With Micro-needling on RT1 Gingival Recession
NCT05470660 UNKNOWN NA
MINST Versus Conventional Subgingival Instrumentation In RT1 Gingival Recession
NCT06044727 COMPLETED NA
Growth Factors in the Treatment of the Multiple Gingival Recessions
NCT05319938 COMPLETED NA
Clinical Evaluation of Tunneled Coronally Advanced Flap v.s Coronally Advanced Flap With Graft for Gingival Recession
NCT06553677 RECRUITING NA
Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2
NCT06842290 NOT_YET_RECRUITING NA
Hyaluronic Acid With Connective Tissue Grafting for Gingival Recession
NCT07291583 ACTIVE_NOT_RECRUITING NA
Xenogenic Collagen Matrix and Subepithelial Connective Tissue Graft in the Treatment of Gingival Recession
NCT04082130 COMPLETED NA
Soft Tissue Profile Following Socket Preservation With Platelet Rich Fibrin Versus Free Gingival Graft
NCT03628170 UNKNOWN NA
Soft Tissue Augmentation Using Deepithelialized Free Gingival Graft Compared to Connective Tissue Graft in Management of Miller Class I and II Gingival Recession.
NCT03213483 COMPLETED NA