Effect of Botulinum Toxin a Injection in Treatment of Recession RT1 and RT2
NCT ID: NCT06842290
Last Updated: 2025-02-25
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.
NOT_YET_RECRUITING
NA
28 participants
INTERVENTIONAL
2025-04-04
2026-10-16
Brief Summary
Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.
Primary outcome is keratinzed tissue width. Researchers will compare Coronally Advanced flap with De-epithelized free gingival graft and Botulinum toxin-A injection in Mentalis muscle with coronally advanced flap with De-epithelized free gingival graft alone .
The outcome will be measured at baseline, after 3 months and after 6 mobths \_medical history
* 3 mm horizontal incisions, then two vertical incisions
* deepitheliztion of anatomical papillae
* superficial and deep incisions
* harvesting DFGG
* Suturing
* BOTOX injection
Related Clinical Trials
Explore similar clinical trials based on study characteristics and research focus.
Effect of Botulinum Toxin-A on Free Gingival Graft
NCT05822323
Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
NCT05823415
Clinical Evaluation of (TCAF) Versus (CAF) Combined With Connective Tissue Graft in the Treatment of Multiple RT2 Gingival Recession Sites
NCT07064603
Gingival Recession (RT1) Treatment With Different Gingival Augmentation Surgeries
NCT05688293
Volumetric Analysis of Alveolar Ridge Contour Using Sub-epithelial Connective Tissue Graft
NCT04482127
Detailed Description
Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.
Conditions
See the medical conditions and disease areas that this research is targeting or investigating.
Study Design
Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.
RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
Review each arm or cohort in the study, along with the interventions and objectives associated with them.
Intervention arm
In this arm principal investigator will preform coronally advanced flap with De-epithelized free gingival graft then will inject Botulinum toxin-A in Mentalis muscle after suturing
Botulinum toxin-A injection
Botulinum toxin-A Injection Mentalis muscle in lower anterior teeth
Control arm
In this arm no injection will be applied only coronally advanced flap with De-epithelized free gingival graft alone
Coronally advanced flap
Coronally Advanced Flap andDe-epithelized Free Gingival Graft
Interventions
Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.
Botulinum toxin-A injection
Botulinum toxin-A Injection Mentalis muscle in lower anterior teeth
Coronally advanced flap
Coronally Advanced Flap andDe-epithelized Free Gingival Graft
Eligibility Criteria
Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.
Inclusion Criteria
* patients ≥18 years
* systemically healthy, full mouth plaque score, full mouth bleeding score ≤ 15% after phase I therapy
* clinical indication and/or patient request for recession coverage
* well motivated patients, maintaining oral hygiene throughout study
Exclusion Criteria
* Smokers' patients
* Teeth with cervical restorations/abrasion.
* Patients had a systemic condition affect blood components and healing
18 Years
ALL
No
Sponsors
Meet the organizations funding or collaborating on the study and learn about their roles.
Cairo University
OTHER
Responsible Party
Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.
Mayar Mostafa Tawfik Ali
Principal investigator
Other Identifiers
Review additional registry numbers or institutional identifiers associated with this trial.
PER3,3,2
Identifier Type: -
Identifier Source: org_study_id
More Related Trials
Additional clinical trials that may be relevant based on similarity analysis.