Effect of Photodynamic Therapy on Soft Tissue Healing After Tooth Extraction at Sites of Periodontal Infection
NCT ID: NCT05664087
Last Updated: 2025-08-24
Study Results
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Basic Information
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COMPLETED
NA
38 participants
INTERVENTIONAL
2023-02-14
2023-11-01
Brief Summary
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
DOUBLE
Study Groups
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Experimental group
Debridement of tooth extraction sockets was assisted by photodynamic equipment
Dental diode laser device Paiwei™（Zhengzhou Gata biotechnology Co.,Ltd.,China） which was 650-670nm with a power of 160mw-220mw.
The tooth extraction sockets were filled with photosensitizer methylene blue. The guide head of the laser periodontal therapy instrument (Dental diode laser device Paiwei™（Zhengzhou Gata biotechnology Co.,Ltd.,China） which was 650-670nm with a power of 160mw-220mw.) was placed in the tooth extraction sockets to probe and move around the tooth extraction sockets for 1 minute. At the end of irradiation, a cotton ball dipped in saline was used to wipe the guide head and rinse the photosensitizer out of the socket
control group
Routine tooth extraction and debridement were performed
No interventions assigned to this group
Interventions
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Dental diode laser device Paiwei™（Zhengzhou Gata biotechnology Co.,Ltd.,China） which was 650-670nm with a power of 160mw-220mw.
The tooth extraction sockets were filled with photosensitizer methylene blue. The guide head of the laser periodontal therapy instrument (Dental diode laser device Paiwei™（Zhengzhou Gata biotechnology Co.,Ltd.,China） which was 650-670nm with a power of 160mw-220mw.) was placed in the tooth extraction sockets to probe and move around the tooth extraction sockets for 1 minute. At the end of irradiation, a cotton ball dipped in saline was used to wipe the guide head and rinse the photosensitizer out of the socket
Other Intervention Names
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Eligibility Criteria
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Inclusion Criteria
* Patients with extensive periodontitis of the whole mouth;
* There was a deep periodontal pocket with PD≥5mm and at least one adjacent tooth at the extraction site;
* Periodontitis was controlled, and the extraction site and adjacent teeth were not in the acute inflammation or infection stage;
* The extraction site has a hopeless prognosis or no preservation value, and it is the first and second molars or maxillary wisdom teeth that erupt in a positive position
Exclusion Criteria
* patients with systemic diseases that may affect the ability of postoperative healing (such as patients with radiotherapy and chemotherapy, history of hematological diseases, and uncontrolled disease) Diabetes mellitus, etc.);
* long-term use of drugs known to affect bone metabolism or mucosal healing such as bisphosphonates and non-steroidal anti-inflammatory drugs;
* smoking \> 10 cigarettes per day;
* root breakage or gingival tear occurred during tooth extraction.
18 Years
65 Years
ALL
No
Sponsors
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The Dental Hospital of Zhejiang University School of Medicine
OTHER
Responsible Party
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Peihui Ding
Principal Investigator
Principal Investigators
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Peihui Ding, Doctor
Role: PRINCIPAL_INVESTIGATOR
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Locations
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The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Hangzhou, Zhejiang, China
Countries
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Other Identifiers
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DHZhejiangU-2022(197)
Identifier Type: -
Identifier Source: org_study_id
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