Combination Therapy Effect of Laser on Wound Healing and Bone Regeneration of Dental Sockets
NCT ID: NCT06552936
Last Updated: 2025-05-16
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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RECRUITING
NA
44 participants
INTERVENTIONAL
2024-12-15
2025-12-31
Brief Summary
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Does laser therapy improve wound healing and bone regeneration after tooth extraction?
Researchers will compare a laser to sham laser therapy to see if the laser enhances wound healing and bone regeneration.
Participants will:
Have exposure to laser or sham laser therapy immediately after tooth extraction Record their pain intensity on days 2, 4, 6 and 14 Visit the clinic after 10 days for follow-up Again, visit the clinic after 4 months for evaluation
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Detailed Description
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Conditions
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Study Design
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RANDOMIZED
PARALLEL
SUPPORTIVE_CARE
DOUBLE
Study Groups
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Low level laser therapy (LLLT)
The LLLT phase will be done with an uninitiated 300-micron tip at 0.5 W in a CW. For this phase, the tip will be kept apart from the targeted tissue by 1mm in the scanning motion.
Diode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
High intensity laser therapy (HILT)
HILT will be done directly after extraction when the extraction socket is filled with blood (without oozing). It will be conducted with the help of an un-initiated 300-micron tip running at the 2-watt (W) power output. It will be in a continuous emission mode (CW).
Diode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
Low level laser therapy+ high intensity laser therapy
The patient will receive a combination of LLLT and HILT.
Diode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
Control
The patient will have the identical treatment as the experimental group but with the laser device in the non-activated phase.
Diode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
Interventions
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Diode Laser 980 nm.
A Diode laser is commonly used in simple surgical procedures on soft tissue, such as skin or mucosa. Its tip can work when non-activated, causing inductive effects, and when activated, it causes the ablation of soft tissue.
Eligibility Criteria
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Inclusion Criteria
* Non-traumatic tooth extraction of the lower jaw is indicated
* Willing for dental implant surgery
* Dental appointments are available at the study place
* Absence of active infection at the extraction site
* Signed informed permission is provided.
Exclusion Criteria
* Smokers
* Those having head and neck radiotherapy
* Those with any sort of acute infection (e.g., periodontal abscess), immune deficiency, or metabolic conditions such as diabetes mellitus and osteoporosis
* Patients will also be eliminated if they have a complication during surgery, such as bleeding or operational difficulties, or if the procedure takes longer than 90 minutes.
21 Years
ALL
Yes
Sponsors
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Universiti Sains Malaysia
OTHER
Sharif Medical Research Center
OTHER
Responsible Party
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Amna Nauman
Professor
Principal Investigators
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Amna N Khan, MPhil
Role: PRINCIPAL_INVESTIGATOR
Sharif Medical and Dental College
Locations
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Sharif Medical and Dental College
Lahore, Punjab Province, Pakistan
Sharif Medical and Dental College
Lahore, , Pakistan
Countries
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Central Contacts
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Facility Contacts
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Other Identifiers
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SMDC/SMRC/242-22
Identifier Type: -
Identifier Source: org_study_id
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