Low-Level Laser Therapy and Injectable Platelet-Rich Fibrin for Thin Gingival Phenotype.

NCT ID: NCT06756854

Last Updated: 2025-01-03

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

PHASE3

Total Enrollment

7 participants

Study Classification

INTERVENTIONAL

Study Start Date

2023-09-12

Study Completion Date

2024-06-15

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

Management of thin gingival phenotype using non-surgical methods (injection of liquid platelet rich fibrin and exposure to low level laser therapy

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

Thin gingival phenotype can lead to recession and root exposure. Liquid prf can be obtained by centrifugion of blood sample on speed 700 rpm for 3 min, then injection of this liquid in the attached gingiva and muco-gingival junction (3 times with 7 days interval) for the first group. The second group will be injected with I-PRF in the same method in addition to exposure to Low Level Laser therapy (after each injection of I-PRF). This method is expected to increase the thickness of the gingiva.

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Periodontal Diseases

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

group1: received I-PRF alone, and group 2: received I-PRF+LLLT
Primary Study Purpose

PREVENTION

Blinding Strategy

SINGLE

Participants
I-PRF biologic product

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

Test group: injectable platelet rich fibrin+ low level laser therapy

patients with thin gingival phenotype (gingival thickness less than 1mm) recieve I-PRF+LLLT radiation just after the injection for 3 sessions with 7 days interval between the sessions.

Group Type ACTIVE_COMPARATOR

injecable platelet rich fibrin, and low level laser therapy radiation.

Intervention Type OTHER

injection of I-PRF+ exposure to LLLT to thin gingival phenotype 3 times with 7 days interval between sessions.

Control group :I-PRF group

patients with thin gingival phenotype received I-PRF alone in 3 sessions, with 7 days interval between the sessions.

Group Type ACTIVE_COMPARATOR

Biologic Agent: injectable platelet rich fibrin.

Intervention Type BIOLOGICAL

injection of I-PRF to thin gingival phenotype 3 times with 7 days interval between sessions.

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

Biologic Agent: injectable platelet rich fibrin.

injection of I-PRF to thin gingival phenotype 3 times with 7 days interval between sessions.

Intervention Type BIOLOGICAL

injecable platelet rich fibrin, and low level laser therapy radiation.

injection of I-PRF+ exposure to LLLT to thin gingival phenotype 3 times with 7 days interval between sessions.

Intervention Type OTHER

Other Intervention Names

Discover alternative or legacy names that may be used to describe the listed interventions across different sources.

Liquid platelet rich fibrin

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* free systimatically good oral hygiene gingival thickness less than 1mm

Exclusion Criteria

* pregnancy or lactation pereiodontitis periodontal surgery orthodontic ttt tooth mobility,bruxism,crowding,missing or supernumerary teeth smoking
Minimum Eligible Age

18 Years

Maximum Eligible Age

40 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Faculty of Dental Medicine for Girls

OTHER_GOV

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Alaa Elsayed

periodontist

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

Learn about the lead researchers overseeing the trial and their institutional affiliations.

Ahmed Eldawy, doctor

Role: PRINCIPAL_INVESTIGATOR

MINDRAY

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

Alaa Elsayed

Cairo, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

P-ME-23-05

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.