Improving Healing in Children After Tooth Extraction Using Laser Therapy or Hyaluronic Acid
NCT ID: NCT07205640
Last Updated: 2025-10-03
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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NOT_YET_RECRUITING
NA
36 participants
INTERVENTIONAL
2025-12-01
2026-12-01
Brief Summary
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Detailed Description
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Post-extraction wound healing and pain perception are related to hostrelated factors such as the patient's immune system, the use of painkillers and antibiotics, the presence of infection in the region, and the atraumatic nature of the procedure. Low-level laser therapy (LLLT) is a widely used adjuvant treatment for wound healing. It is based on the idea that exposure to a specific wavelength can alter cellular behavior, resulting in both an increase in cell number and an increase in cell metabolism. Aside from not having any negative effects, LLLT is an a thermic, photobiological, and nondestructive therapy approach.
HA it is an important component of the extracellular matrix and a constituent of the neural, connective, and epithelial tissues. Among the many biological effects of HA are its functions in cell differentiation, wound healing, inflammation, embryological development, and viscoelasticity.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Low-Level Laser Therapy (LLLT)
Participants in this arm will receive low-level laser therapy (LLLT) immediately after extraction of the first permanent molar.
Low-Level Laser Therapy
A 980 nm diode laser will be applied immediately after extraction of the first permanent molar. The laser will be used in continuous mode at 0.5 W, with a total energy of 300 J, applied for 60 seconds at three points around the extraction socket.
Hyaluronic Acid (HA)
Participants in this arm will receive hyaluronic acid (HA) immediately after extraction of the first permanent molar.
Hyaluronic Acid (HA)
Hyaluronic acid gel will be applied directly into the extraction socket immediately after tooth removal.
Interventions
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Low-Level Laser Therapy
A 980 nm diode laser will be applied immediately after extraction of the first permanent molar. The laser will be used in continuous mode at 0.5 W, with a total energy of 300 J, applied for 60 seconds at three points around the extraction socket.
Hyaluronic Acid (HA)
Hyaluronic acid gel will be applied directly into the extraction socket immediately after tooth removal.
Eligibility Criteria
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Inclusion Criteria
2. Children of both genders.
3. Children with badly decayed first permanent molar beyond repair and indicated for extraction.
4. Parents acceptance to participate in the study.
Exclusion Criteria
2. Uncooperative children.
3. Children who will not attend the follow up visits
6 Years
10 Years
ALL
Yes
Sponsors
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Cairo University
OTHER
Responsible Party
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Mona Ali Abd Elhafiz Ali
Bachelor Degree in Oral and Dental Medicine
Principal Investigators
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Mona Ali Abd Elhafiz, BDS
Role: PRINCIPAL_INVESTIGATOR
Cairo University
Locations
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Faculty Of Oral & Dental Medicine - Cairo University
Giza, EL Menial, Egypt
Countries
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Central Contacts
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Related Links
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Background reference on low-level laser therapy and wound healing in dentistry.
Other Identifiers
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LLLTvsHA-2025
Identifier Type: -
Identifier Source: org_study_id
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