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Efficacy of Er:YAG Laser in Removing Impacted Mandibular Third Molars

NCT ID: NCT07297043

Last Updated: 2025-12-29

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2024-09-25

Study Completion Date

2025-01-29

Brief Summary

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This randomized controlled clinical trial aims to evaluate the efficacy of the Er:YAG laser in the removal of impacted mandibular third molars compared to the conventional surgical technique. The study assesses surgical efficiency, postoperative pain, swelling, trismus, and overall patient recovery. The goal is to determine whether the Er:YAG laser provides a safer and less traumatic alternative to traditional bone-cutting methods during third molar surgery.

Detailed Description

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Impacted mandibular third molars are among the most commonly extracted teeth, and conventional surgical removal often involves bone cutting using rotary instruments, which may increase postoperative morbidity. Laser-assisted surgery, particularly using the Er:YAG laser, has been proposed as a minimally invasive alternative with potential benefits such as reduced thermal damage, improved healing, and less postoperative discomfort.

This study compares Er:YAG laser-assisted bone removal with the conventional bur technique in terms of operative time, intraoperative ease, and postoperative outcomes including pain, edema, and trismus. Patients meeting the eligibility criteria are randomly allocated into two groups: a laser-assisted surgery group and a conventional surgery group. Standardized measurements and follow-up assessments are conducted to evaluate clinical outcomes and determine the effectiveness and safety of the Er:YAG laser in third molar surgery.

Conditions

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Impacted Mandibular Third Molar

Keywords

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Third Molar Surgery Er:YAG Laser Laser-Assisted Surgery Oral Surgery

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Participants are randomly assigned into two parallel groups: Er:YAG laser-assisted surgery and conventional rotary instrument surgery.
Primary Study Purpose

TREATMENT

Blinding Strategy

NONE

No masking was performed because both the surgeon and the participants were aware of the intervention type.

Study Groups

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Er:YAG Laser Group

Participants in this group will undergo impacted mandibular third molar surgery using the Er:YAG laser for bone removal.

Group Type EXPERIMENTAL

Er:YAG laser

Intervention Type DEVICE

Er:YAG laser (2940 nm) used for bone cutting during impacted mandibular third molar surgery.

Conventional Rotary Instrument Group

Participants in this group will undergo impacted mandibular third molar surgery using conventional rotary instruments (bur and handpiece) for bone cutting.

Group Type ACTIVE_COMPARATOR

Conventional Rotary Instruments Surgery

Intervention Type PROCEDURE

Conventional rotary instruments used for bone removal during surgical extraction of impacted mandibular third molars.

Interventions

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Er:YAG laser

Er:YAG laser (2940 nm) used for bone cutting during impacted mandibular third molar surgery.

Intervention Type DEVICE

Conventional Rotary Instruments Surgery

Conventional rotary instruments used for bone removal during surgical extraction of impacted mandibular third molars.

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* • Adults aged 20-30 years requiring surgical extraction of a mesioangular impacted mandibular third molar.

* Healthy individuals with no systemic diseases that may influence bone metabolism or wound healing.
* Good oral hygiene and absence of local infection at the surgical site.
* No contraindications to local anesthesia, surgical extraction, or use of the Er:YAG laser.
* Radiographic evidence confirming normal bone structure without cysts or pathological lesions.
* Willingness to participate and ability to provide informed consent.

Exclusion Criteria

* • Systemic medical conditions affecting bone healing or postoperative response (e.g., uncontrolled diabetes, immunodeficiency, metabolic bone disorders).

* Current or recent use of medications influencing bone remodeling (e.g., bisphosphonates, corticosteroids, immunosuppressants).
* Heavy smoking (\>10 cigarettes/day).
* Pregnant or breastfeeding females.
* Poor oral hygiene, active infection, or pericoronitis at the surgical site.
* Previous surgery, trauma, or pathology in the mandibular third molar region.
* Known allergies or contraindications to any material or procedure used in the study.
Minimum Eligible Age

18 Years

Maximum Eligible Age

30 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

No

Sponsors

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Alexandria University

OTHER

Sponsor Role lead

Responsible Party

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Karim Anwer Ahmed Nazmy

Postgraduate Researcher, Oral Laser Applications

Responsibility Role PRINCIPAL_INVESTIGATOR

Principal Investigators

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Karim Elhaw, MSc (Oral Laser Applications)

Role: PRINCIPAL_INVESTIGATOR

Alexandria University

Locations

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Faculty of Dentistry, Alexandria University

Alexandria, Alexandria Governorate, Egypt

Site Status

Countries

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Egypt

Other Identifiers

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ALEXDEN-KA-IMP_M3-2025

Identifier Type: -

Identifier Source: org_study_id