Advanced Platelet-rich Fibrin Combined With Open Debridement in Management of Suprabony Periodontal Defects

NCT ID: NCT05730153

Last Updated: 2023-03-27

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

COMPLETED

Clinical Phase

PHASE4

Total Enrollment

30 participants

Study Classification

INTERVENTIONAL

Study Start Date

2021-11-21

Study Completion Date

2022-07-26

Brief Summary

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in this clinical trial, patients with periodontal defects will be treated with advanced platelet-rich fibrin in conjunction with open debridement

Detailed Description

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two groups of patients with suprabony defects, one will be treated with advanced platelet-rich fibrin in conjunction with open debridement and the other will be treated with open debridement alone. subjects will be evaluated for evidence of bone formation after 6 months of therapy

Conditions

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Periodontitis, Adult

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Caregivers Investigators Outcome Assessors

Study Groups

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group 1

Group Type ACTIVE_COMPARATOR

advanced PRF

Intervention Type BIOLOGICAL

advanced PRF+ surgery

group 2

Group Type SHAM_COMPARATOR

advanced PRF

Intervention Type BIOLOGICAL

advanced PRF+ surgery

Interventions

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advanced PRF

advanced PRF+ surgery

Intervention Type BIOLOGICAL

Eligibility Criteria

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Inclusion Criteria

* patients with periodontal suprabony defects.

Exclusion Criteria

* pregnant females.
* smokers.
* systemic disease that contraindicate surgery
Minimum Eligible Age

18 Years

Maximum Eligible Age

60 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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October University for Modern Sciences and Arts

OTHER

Sponsor Role lead

Responsible Party

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Naglaa Elwakeel

professor

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Al-Azhar University, Faculty of Dentistry

Cairo, , Egypt

Site Status

Countries

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Egypt

Other Identifiers

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OMD 3-22

Identifier Type: -

Identifier Source: org_study_id

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