Furcation Treatment With L-PRF and aPDT

NCT ID: NCT04842188

Last Updated: 2021-06-24

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

Get a concise snapshot of the trial, including recruitment status, study phase, enrollment targets, and key timeline milestones.

Recruitment Status

COMPLETED

Clinical Phase

NA

Total Enrollment

24 participants

Study Classification

INTERVENTIONAL

Study Start Date

2020-07-28

Study Completion Date

2021-04-30

Brief Summary

Review the sponsor-provided synopsis that highlights what the study is about and why it is being conducted.

To treat grade II periodontally diseased furcation areas Leukocyte-Platelet Rich Fibrin (L-PRF) combined with antimicrobial Photo-Dynamic Therapy (a-PDT) was used.

Detailed Description

Dive into the extended narrative that explains the scientific background, objectives, and procedures in greater depth.

randomized, triple-blinded study (patient, clinician and biostatistician). Twenty-four patients with Grade II furcation involvement were recruited in this study.

Control group only received L-PRF, while study group used a combination of L-PRF and aPDT Attachment level, pocket depth, horizontal component and gingival recession, also radiographic Bone depth, width, height and volume were were recorded at baseline and postoperatively after 6 months

Conditions

See the medical conditions and disease areas that this research is targeting or investigating.

Furcation Defects

Study Design

Understand how the trial is structured, including allocation methods, masking strategies, primary purpose, and other design elements.

Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

TRIPLE

Participants Investigators Outcome Assessors

Study Groups

Review each arm or cohort in the study, along with the interventions and objectives associated with them.

L-PRF

Leukocyte platelet rich fibrin as a sole graft material in class II furcation

Group Type ACTIVE_COMPARATOR

L-PRF

Intervention Type PROCEDURE

surgical open flap debridement followed by L-PRF alone

L-PRF with aPDT

Leukocyte platelet rich fibrin combined with antibacterial photodynamic therapy in class II furcation

Group Type ACTIVE_COMPARATOR

L-PRF with aPDT

Intervention Type PROCEDURE

surgical open flap debridement followed by L-PRF with aPDT

Interventions

Learn about the drugs, procedures, or behavioral strategies being tested and how they are applied within this trial.

L-PRF with aPDT

surgical open flap debridement followed by L-PRF with aPDT

Intervention Type PROCEDURE

L-PRF

surgical open flap debridement followed by L-PRF alone

Intervention Type PROCEDURE

Eligibility Criteria

Check the participation requirements, including inclusion and exclusion rules, age limits, and whether healthy volunteers are accepted.

Inclusion Criteria

* Grade II furcation involvement
* age range 18- 50 years
* 3 mm or more vertical probing depth

Exclusion Criteria

* systemic disease
* abnormal clotting and bleeding
* smokers,
* root caries or restoration
* Grade II mobility
* periapical lesions
Minimum Eligible Age

32 Years

Maximum Eligible Age

48 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

Meet the organizations funding or collaborating on the study and learn about their roles.

Kafrelsheikh University

OTHER

Sponsor Role lead

Responsible Party

Identify the individual or organization who holds primary responsibility for the study information submitted to regulators.

Walid Elamrousy

lecturer of oral medicine and periodontology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

Explore where the study is taking place and check the recruitment status at each participating site.

faculty of dentistry, kafrelsheikh University

Kafr ash Shaykh, , Egypt

Site Status

Countries

Review the countries where the study has at least one active or historical site.

Egypt

Other Identifiers

Review additional registry numbers or institutional identifiers associated with this trial.

elamrousy2020

Identifier Type: -

Identifier Source: org_study_id

More Related Trials

Additional clinical trials that may be relevant based on similarity analysis.

Growth Factors Release of PRF and PRGF
NCT02447510 COMPLETED PHASE3