Effect of Albumin Platelet-Rich Fibrin or Leucocyte- Platelet-Rich Fibrin on Immediate Implant

NCT ID: NCT06863051

Last Updated: 2025-08-01

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

RECRUITING

Clinical Phase

NA

Total Enrollment

20 participants

Study Classification

INTERVENTIONAL

Study Start Date

2025-08-20

Study Completion Date

2027-02-10

Brief Summary

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The objective of this study will be to compare between Immediate Implant grafted with xenograft and Alb-PRF gel versus xenograft with L-PRF.

Detailed Description

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The objective of this study will be to compare between xenograft with Alb-PRF gel and xenograft with L-PRF ( L-PRF Block ) in the aspects of :

* Peri-implant vertical defect depth.
* Crestal bone level.
* Bucco-lingual bone width.
* Keratinized tissue width

Conditions

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Immediate Implant Placement

Study Design

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Allocation Method

RANDOMIZED

Intervention Model

PARALLEL

Primary Study Purpose

TREATMENT

Blinding Strategy

SINGLE

Outcome Assessors

Study Groups

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Albumin-PRF group

Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel

Group Type EXPERIMENTAL

Immediate Implant Placement and Alb-PRF

Intervention Type PROCEDURE

Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel

L-PRF group

Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF ( L-PRF Block )

Group Type EXPERIMENTAL

Immediate Implant Placement and L-PRF

Intervention Type PROCEDURE

Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF

Interventions

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Immediate Implant Placement and Alb-PRF

Immediate Implant Placement in lower molar region, Grafted with Xenograft and Albumin PRF Gel

Intervention Type PROCEDURE

Immediate Implant Placement and L-PRF

Immediate Implant Placement in lower molar region, Grafted with Xenograft and L-PRF

Intervention Type PROCEDURE

Eligibility Criteria

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Inclusion Criteria

* The presence of non-restorable mandibular molar.
* Patient 18-45 years old
* Intact buccal and lingual walls
* Good oral hygiene.
* Prescence of sufficient restorative space.
* Jumping gap more than 2 mm.

Exclusion Criteria

* Proximity of anatomical structures
* Acute localized infection (suppuration at the surgical field)
* Patients on chemotherapy or radiotherapy.
* Patients who have systemic disorders (diseases) {diabetes mellitus, autoimmune disease, …etc},
* Pregnant patients.
* Smoking and Alcohols.
* Presence of periapical pathology affecting the neighboring teeth.
Minimum Eligible Age

18 Years

Maximum Eligible Age

45 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes

Sponsors

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Kafrelsheikh University

OTHER

Sponsor Role lead

Responsible Party

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Mostafa Fayed

Demonstrator of Periodontology

Responsibility Role PRINCIPAL_INVESTIGATOR

Locations

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Kafrelsheikh University, Faculty of Dentistry

Kafr ash Shaykh, Kafrelsheikh, Egypt

Site Status RECRUITING

Countries

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Egypt

Central Contacts

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Mostafa Mohamed Fayed, Demonstrator of Periodontology

Role: CONTACT

0201004668099

Facility Contacts

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Enas Ahmed Elgendy, Dean of Faculty of Dentistry

Role: primary

0201003508797

Other Identifiers

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KFSIRB200-531

Identifier Type: -

Identifier Source: org_study_id

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