A Registered Cohort Study on Color Discrimination Deficit Associated With Neurodegenerative Disorders.

Study Results

Results pending

The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.

Basic Information

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Recruitment Status

UNKNOWN

Total Enrollment

500 participants

Study Classification

OBSERVATIONAL

Study Start Date

2018-01-01

Study Completion Date

2025-07-01

Brief Summary

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Color discrimination deficit is a common manifestation of Alzheimer's disease (AD). However, the pathophysiology of this dysfunction remains poorly understood. The aim of the present study was to evaluate color discrimination using the Farnsworth-Munsell 100 hue test in patients with AD and mild cognitive impairment (MCI), compared with age-matched control subjects. As a secondary aim, we evaluated whether the outcomes of these visual tests were associated with cognitive.

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Detailed Description

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Conditions

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Neurodegenerative Disorders

Study Design

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Observational Model Type

COHORT

Study Time Perspective

PROSPECTIVE

Study Groups

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Color discrimination deficit

Data collection

Intervention Type OTHER

Neuropsychological assessment, FM-1OO, brain MRI, electroencephalogram and biomarker datas will be collected

Without Color discrimination deficit

Data collection

Intervention Type OTHER

Neuropsychological assessment, FM-1OO, brain MRI, electroencephalogram and biomarker datas will be collected

Interventions

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Data collection

Neuropsychological assessment, FM-1OO, brain MRI, electroencephalogram and biomarker datas will be collected

Intervention Type OTHER

Eligibility Criteria

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Inclusion Criteria

* All patients underwent extensive clinical examination including thorough neurological and somatic examination by a specialized neurologist or geriatrician and extensive neuropsychological examination by a trained psychologist. AD was diagnosed according to the NINCDS-ADRDA criteria.

Exclusion Criteria

* We excluded individuals with noncompensated somatic illnesses, a history of a psychiatric disorder, color blindness, ophthalmological pathology, severe cranial trauma, focal neurological signs or magnetic resonance imaging examinations suggestive of cerebrovascular disturbances.

Minimum Eligible Age

30 Years

Maximum Eligible Age

80 Years

Eligible Sex

ALL

Accepts Healthy Volunteers

Yes