Effect of Precise Grip Strength Training on PICC Catheter-Related Thrombosis in Cancer Patients

NCT ID: NCT05638048

Last Updated: 2023-02-03

Basic Information

• Recruitment Status: COMPLETED
• Clinical Phase: NA
• Total Enrollment: 270 participants
• Study Classification: INTERVENTIONAL
• Study Start Date: 2022-07-10
• Study Completion Date: 2023-01-10

Brief Summary

In this study, color Doppler ultrasound diagnostic instrument and electronic grip device were used to determine the best grip strength of patients with tumor PICC catheterization, formulate precise and standardized grip strength training guidance for them, provide personalized functional exercise health education, and observe the impact of precise grip strength training guidance on Peripheral central venous catheter-associated thrombosis. To provide a reference for clinical prevention of Peripheral central venous catheter-associated thrombosis in the future.

Conditions

Lung Cancer; Stomach Cancer; Breast Cancer; Liver Cancer; Colon Cancer; Rectal Cancer

Study Design

• Allocation Method: RANDOMIZED
• Intervention Model: PARALLEL
• Primary Study Purpose: PREVENTION
• Blinding Strategy: SINGLE

Study Groups

The control group

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Group Type: ACTIVE_COMPARATOR

Health education on routine grip strength training

Intervention Type: BEHAVIORAL

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Experiment 1 set

Patients were routinely implanted with PICC, and the optimal duration-relaxation time of grip strength training was adopted on the basis of health education in the control group.

Group Type: EXPERIMENTAL

Use maximum strength grip training

Intervention Type: BEHAVIORAL

Patients were routinely implanted with PICC, and on the basis of health education in the control group, the best continuous-relaxation time, frequency and maximum grip strength of patients were used for grip strength training.

Experiment 2 set

On the basis of control group

1. Determine the best grip strength On the basis of the control group, color Doppler ultrasound and electronic grip force were used to record the optimal grip strength of patients to achieve effective blood flow velocity before and 24 hours after PICC insertion.

2. Design precise grip strength training guidance program On the basis of the control group, the patients were instructed to perform grip strength training according to the determined best grip strength and the best duration of clenching and relaxation time.

Group Type: EXPERIMENTAL

Precision grip training

Intervention Type: BEHAVIORAL

First determine patients for holding the ball movement should reach the effective blood flow velocity and best duration - relaxation, and USES the electronic grips and color doppler ultrasonic diagnostic apparatus, for individual patients to choose the best grip the efforts and training, to form the best grip the training plan, and observe the scheme for Peripheral central venous catheter-associated thrombosis prevention effect.

Interventions

Precision grip training

First determine patients for holding the ball movement should reach the effective blood flow velocity and best duration - relaxation, and USES the electronic grips and color doppler ultrasonic diagnostic apparatus, for individual patients to choose the best grip the efforts and training, to form the best grip the training plan, and observe the scheme for Peripheral central venous catheter-associated thrombosis prevention effect.

Intervention Type: BEHAVIORAL

Use maximum strength grip training

Patients were routinely implanted with PICC, and on the basis of health education in the control group, the best continuous-relaxation time, frequency and maximum grip strength of patients were used for grip strength training.

Intervention Type: BEHAVIORAL

Health education on routine grip strength training

Patients were routinely implanted with PICC and received routine health education. The content of health education included face-to-face language explanation of the whole process of catheter knowledge, issuing catheter maintenance manual, issuing ordinary grip ball and telling how to use it, and follow-up.

Intervention Type: BEHAVIORAL

Eligibility Criteria

Inclusion Criteria

• Cancer patients undergoing chemotherapy throughout their treatment in our hospital
• Patients with PICC implanted for the first time and maintained at our hospital;
• Age 18-60 years;
• Normal cognitive function;
• the clenching movement is barrier-free;
• The material and performance of PICC catheter are silicone three-way valve catheter;
• Catheter placement under the guidance of portable color Doppler ultrasound diagnostic instrument;
• Voluntarily participate and sign the informed consent form.

Exclusion Criteria

• Patients treated with combined radiotherapy;
• Patients with coagulation dysfunction;
• Patients who need to use anticoagulant drugs due to underlying diseases;
• Puncture times more than 1 time;
• The blood flow velocity of catheterization vessel in calm state was less than 4.78cm/s.

• Minimum Eligible Age: 18 Years
• Maximum Eligible Age: 60 Years
• Eligible Sex: ALL
• Accepts Healthy Volunteers: No

Sponsors

Junyan Zhao

OTHER

Sponsor Role: lead

Responsible Party

Junyan Zhao

Principal investigator

Responsibility Role: SPONSOR_INVESTIGATOR

Principal Investigators

Junyan Zhao, Master

Role: STUDY_DIRECTOR

Qianfoshan Hospital

Yuanjing Qiao, Master

Role: PRINCIPAL_INVESTIGATOR

Shandong University of Traditional Chinese Medicine

Locations

Qianfoshan Hospital

Jinan, Shandong, China

Countries

China

Other Identifiers

YXLL-KY-2022(057)

Identifier Type: -

Identifier Source: org_study_id