Muscle Strength Training for Older Adults With Type II Diabetes
NCT ID: NCT03280758
Last Updated: 2017-09-12
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
NA
60 participants
INTERVENTIONAL
2017-10-01
2019-08-30
Brief Summary
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60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group.
Muscle strengthening group will receive resistance training 3 times per week (1 hour/session).
The control group will not receive any training but can continue usual medical care and daily activities.
Primary outcomes: glycemic control and lipid profile Secondary outcomes: muscle mass and strength, and functional capacity Data will be collected at baseline (pre-test) and after a 4-month intervention (post-test).
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Detailed Description
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This is a single-blinded, randomized controlled trial. 60 subjects will be randomly allocated to either a muscle strengthening group or a no exercise control group.
Information on demographic characteristics, body composition, muscle strength, functional capacity and glycemic control will be collected at baseline (pre-test) and after a 4-month intervention (post-test). Muscle strengthening group will receive resistance training 3 times per week (1 hour/session).
The control group will not receive any training but can continue usual medical care and daily activities.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
SINGLE
Study Groups
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Muscle strengthening group
Participants will be required to perform muscle strengthening exercises 3 hours per week. Close kinetic chain exercises will be performed progressively according to the ACSM guidelines over the 4-month intervention period. The exercise intervention will be conducted by an experienced sports trainer.
Muscle Strengthening exercises
Participants will be required to participate in resistance training 3 hours per week.
Control group
No exercise training.
No interventions assigned to this group
Interventions
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Muscle Strengthening exercises
Participants will be required to participate in resistance training 3 hours per week.
Eligibility Criteria
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Inclusion Criteria
* 60-75 years old
* ability to perform exercise
Exclusion Criteria
* severe obesity (BMI ≥ 48kg/m2)
* insulin pump user
* coronary heart disease history
* chronic obstructive pulmonary disease
* advanced neuropathy
* learning or mental disorder, or
* any other diseases that prevent subjects from exercising safely.
* Those who participate in regular resistance or aerobic exercises will also be excluded.
60 Years
75 Years
ALL
No
Sponsors
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The University of Hong Kong
OTHER
Responsible Party
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Shirley S.M. Fong
Dr
Principal Investigators
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Siu Ming Fong, PhD
Role: PRINCIPAL_INVESTIGATOR
The University of Hong Kong
Central Contacts
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References
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Nolan CJ, Damm P, Prentki M. Type 2 diabetes across generations: from pathophysiology to prevention and management. Lancet. 2011 Jul 9;378(9786):169-81. doi: 10.1016/S0140-6736(11)60614-4. Epub 2011 Jun 24.
Leenders M, Verdijk LB, van der Hoeven L, Adam JJ, van Kranenburg J, Nilwik R, van Loon LJ. Patients with type 2 diabetes show a greater decline in muscle mass, muscle strength, and functional capacity with aging. J Am Med Dir Assoc. 2013 Aug;14(8):585-92. doi: 10.1016/j.jamda.2013.02.006. Epub 2013 Mar 26.
Shishikura K, Tanimoto K, Sakai S, Tanimoto Y, Terasaki J, Hanafusa T. Association between skeletal muscle mass and insulin secretion in patients with type 2 diabetes mellitus. Endocr J. 2014;61(3):281-7. doi: 10.1507/endocrj.ej13-0375. Epub 2014 Jan 10.
Dunstan DW, Daly RM, Owen N, Jolley D, De Courten M, Shaw J, Zimmet P. High-intensity resistance training improves glycemic control in older patients with type 2 diabetes. Diabetes Care. 2002 Oct;25(10):1729-36. doi: 10.2337/diacare.25.10.1729.
American Diabetes Association. Diabetes mellitus and exercise. Diabetes Care. 2000 Jan;23 Suppl 1:S50-4. No abstract available.
Albright A, Franz M, Hornsby G, Kriska A, Marrero D, Ullrich I, Verity LS. American College of Sports Medicine position stand. Exercise and type 2 diabetes. Med Sci Sports Exerc. 2000 Jul;32(7):1345-60. doi: 10.1097/00005768-200007000-00024.
Black LE, Swan PD, Alvar BA. Effects of intensity and volume on insulin sensitivity during acute bouts of resistance training. J Strength Cond Res. 2010 Apr;24(4):1109-16. doi: 10.1519/JSC.0b013e3181cbab6d.
Baldi JC, Snowling N. Resistance training improves glycaemic control in obese type 2 diabetic men. Int J Sports Med. 2003 Aug;24(6):419-23. doi: 10.1055/s-2003-41173.
Other Identifiers
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02
Identifier Type: -
Identifier Source: org_study_id
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