CBD (Cannabidiol) Intraoral Application and TMD (Temporomandibular Disorders)
NCT ID: NCT05562635
Last Updated: 2023-07-21
Study Results
The study team has not published outcome measurements, participant flow, or safety data for this trial yet. Check back later for updates.
Basic Information
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UNKNOWN
PHASE2/PHASE3
30 participants
INTERVENTIONAL
2023-07-18
2023-08-30
Brief Summary
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Detailed Description
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CBD intraoral application therapy seems promising in that field. Patients attending The Department of TMD in Zabrze, Polska will be randomly divided into two groups: experimental and placebo. sEMG activity values will be compared during 14 and 30 days therapy with polymers. the efficacy of the cannabis cream used in the study. Positive results will confirm the efficacy of CBD relaxing properties used in the study, compared to placebo.
Conditions
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Study Design
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RANDOMIZED
PARALLEL
TREATMENT
TRIPLE
Study Groups
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5 % polymers with CBD application
Bilateral application of 5% polymer gel with CBD intraorally, on the masseter muscle
5% polymer gel with CBD application
Bilateral application of 5% polymer gel with CBD intraorally, on the masseter muscle
10 % polymers with CBD application
Bilateral application of 10% polymer gel with CBD intraorally, on the masseter muscle
10% polymer gel with CBD application
Bilateral application of 10% polymer gel with CBD intraorally, on the masseter muscle
Placebo group
Application of polymers without CBD on the masseter muscles, bilaterally
Placebo intervention
Application of placebo without CBD
Interventions
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5% polymer gel with CBD application
Bilateral application of 5% polymer gel with CBD intraorally, on the masseter muscle
10% polymer gel with CBD application
Bilateral application of 10% polymer gel with CBD intraorally, on the masseter muscle
Placebo intervention
Application of placebo without CBD
Eligibility Criteria
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Inclusion Criteria
* Age ≥18 and ≤ 60
* Good general health,
* Temporomandibular disorder-positive RDC/TMD examination for group Ia and Ib
* Presence of all teeth (with the exception of the third molars)
Exclusion Criteria
* Hypersensitivity to substances to be used in the study
* Wounds intra oral cavity
* Addiction to cannabis
* Patients being treated with analgesic drugs and/or drugs that affect muscle function
18 Years
60 Years
ALL
Yes
Sponsors
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Medical University of Silesia
OTHER
Responsible Party
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Locations
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Department of TMD
Zabrze, , Poland
Countries
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Facility Contacts
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Other Identifiers
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CBD (Cannabidiol)
Identifier Type: -
Identifier Source: org_study_id
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